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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
SRPK1
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "SRPK1" in MCE Product Catalog:
17
17 Publications Verification
Synonyms: SRPK inhibitor
Target:
Research Areas:
SRPIN340 is an ATP-competitive serine-arginine-rich protein kinase (SRPK) inhibitor, with a Ki of 0.89 μM for SRPK1.
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13 Cited Publications
Cat. No.: HY-117661
CAS No.: 1818389-84-2
Research Areas:
SPHINX31 is a potent and selective SRPK1 inhibitor, with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). SPHINX31 also decreases the mRNA expression of pro-angiogenic VEGF-A165a isoform. SPHINX31 can be used to research neovascular eye disease [1] .
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6 Cited Publications
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SRPKIN-1 is a covalent and irreversible SRPK1/2 inhibitor with IC50s of 35.6 and 98 nM, respectively. Anti-angiogenesis effect [1].
1
1 Cited Publications
MSC-1186, a chemical probe, is a highly selective pan-SRPK inhibitor. MSC-1186 has activity for SRPK1, SRPK2 and SRPK3 with IC50 values of 2.7 nM, 81 nM and 0.6 nM, respectively. MSC-1186 can be used for the research of cancer [1].
Cat. No.: HY-160586
CAS No.: 2408444-93-7
Srpk1-IN-1 (compound 12) is a potent inhibitor of SRPK1, with IC50 of 0.3 nM [1].
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SRPIN803 is a potent CK2 and SRPK1 dual inhibitor, with IC50s of 203 nM and 2.4 μM, respectively. SRPIN803 exhibits antiangiogenic activity. SRPIN803 can be used for the research of age-related macular degeneration [1] .
Cat. No.: HY-E70863
SRPK1 (serine-arginine protein kinase 1) is a protein kinase that specifically phosphorylates proteins containing serine-arginine-rich domains. SRPK1 Recombinant Human Active Protein Kinase is a recombinant SRPK1 protein that can be used to study SRPK1-related functions [1].
SPHINX is a selective SRPK1 inhibitor with an IC50 value of 0.58 μM. SPHINX effectively reduces Choroidal Neovascularization (CNV) in vivo. SPHINX can be used for the research of (age-related macular degenaration) AMD [1].
Cat. No.: HY-RS13777
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SRPK1 Human Pre-designed siRNA Set A contains three designed siRNAs for SRPK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17173
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Srpk1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Srpk1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-113831
CAS No.: 1005784-60-0
LK1/2-IN-3 (compound 3) is a potent and selective CLK1 and CLK2 inhibitor with IC50 values of 1.1, 2.1, 130, 260, 260 nM for CLK1, CLK2, SRPK1, SRPK2, SRPK3, respectively. CLK1/2-IN-3 shows anti-proliferative activity. CLK1/2-IN-3 reduces the levels of endogenous phosphorylated SR proteins and increases the expression of S6K mRNAs [1].
Cat. No.: HY-RS23623
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Srpk1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Srpk1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-E70804
SRPK1 (serine-arginine protein kinase 1) is a protein kinase that specifically phosphorylates proteins containing serine-arginine-rich domains. Biotin-SRPK1 Recombinant Human Active Protein Kinase is a recombinant SRPK1 protein that can be used to study SRPK1-related functions, and is biotinylated [1].
Cat. No.: HY-160587
CAS No.: 2095397-52-5
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Antiangiogenic agent 5 (compound 17) has anti-angiogenic activity. Antiangiogenic agent 5 show inhibition to SRPK1, with IC50 of 1.3 nM [1].
Cat. No.: HY-P705641
Purity: ≥ 80%, as determined by reducing SDS-PAGE .
Synonyms: SRPK1; Serine/Arginine-Rich Splicing Factor Kinase 1; SRSF Protein Kinase 1; SR-Protein-Specific Kinase 1; SFRS Protein Kinase 1; Non-Specific Serine/Threonine Protein Kinase; SFRSK1; Serine/Threonine-Protein Kinase SRPK1; Serine/Arginine-Rich Protein-Spe
Cat. No.: HY-P705886
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: SRPK1; Serine/Arginine-Rich Splicing Factor Kinase 1; SRSF Protein Kinase 1; SR-Protein-Specific Kinase 1; SFRS Protein Kinase 1; Non-Specific Serine/Threonine Protein Kinase; SFRSK1; Serine/Threonine-Protein Kinase SRPK1; Serine/Arginine-Rich Protein-Spe
Cat. No.: HY-P87087
Synonyms: Serine/arginine rich protein specific kinase 1 antibody; Serine/arginine rich splicing factor kinase 1 antibody; Serine/arginine-rich protein-specific kinase 1 antibody; Serine/threonine protein kinase SRPK1 antibody; Serine/threonine-protein kinase SRPK1 antibody; SFRS protein kinase 1 antibody; SFRSK1 antibody; SR protein kinase 1 antibody; SR protein specific kinase 1 antibody; SR-protein-specific kinase 1 antibody; Serine/arginine rich protein specific kinase 1 antibody; Serine/arginine rich splicing factor kinase 1 antibody; Serine/arginine-rich protein-specific kinase 1 antibody; Serine/threonine protein kinase SRPK1 antibody; Serine/threonine-protein kinase SRPK1 antibody; SFRS protein kinase 1 antibody; SFRSK1 antibody; SR protein kinase 1 antibody; SR protein specific kinase 1 antibody; SR-protein-specific kinase 1 antibody; SRPK1 antibody; SRPK1_HUMAN antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
