6 Results for "

Ser1292

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Ser1292" in MCE Product Catalog:

Cat. No.: HY-12282
CAS No.: 1536200-31-3
Purity:  99.72%
Target:  

LRRK2

Research Areas:  

Neurological Disease

GNE-9605 is a potent, orally active, selective Leucine-rich repeat kinase 2 (LRRK2) inhibitor with an IC50 value of 18.7 nM. GNE-9605 inhibits LRRK2 Ser1292 autophosphorylation. GNE-9605 can be used in research of Parkinson's disease (PD) .
loading...
    loading...
Cat. No.: HY-P10519
CAS No.: 2676889-05-5
Research Areas:  

Infection

Brevicidine is an antimicrobial peptide with selective bactericidal activity against Gram-negative pathogens. Brevicidine disrupts bacterial morphology by binding to lipopolysaccharide (LPS) on the bacterial cell membrane to form pores. Brevicidine causes dissipation of intracellular proton motive force, outer membrane damage, inhibition of ATP biosynthesis and reactive oxygen species accumulation in bacterial cells. As a sensitizer, Brevicidine exerts synergistic activity when combined with a variety of conventional antibiotics .
loading...
    loading...
Cat. No.: HY-151441
CAS No.: 2892451-45-3
Target:  

LRRK2

Research Areas:  

Neurological Disease

LRRK2-IN-5 (compound 25) is a potent, orally active, selective leucine rich repeat protein kinase 2 gene (LRRK2) inhibitor with IC50 values of 1.2 and 16 μM for GS LRRK2 and WT LRRK2, respectively. LRRK2-IN-5 inhibits LRRK2 Ser1292 and Ser925 autophosphorylation. LRRK2-IN-5 can cross the blood-brain barrier .
loading...
    loading...
Cat. No.: HY-151444
CAS No.: 2892451-17-9
Target:  

LRRK2

Research Areas:  

Neurological Disease

LRRK2-IN-6 (compound 22) is a potent, orally active, selective leucine rich repeat protein kinase 2 gene (LRRK2) inhibitor with IC50 values of 4.6 and 49 μM for GS LRRK2 and WT LRRK2, respectively. LRRK2-IN-6 inhibits LRRK2 Ser1292 and Ser925 autophosphorylation. LRRK2-IN-6 can cross the blood-brain barrier .
loading...
    loading...
Cat. No.: HY-P0007
CAS No.: 60731-46-6
Synonyms: Carbocalcitonin
Target:  

Drug Intermediate

Research Areas:  

Metabolic Disease

Elcatonin (Carbocalcitonin) is a synthetic analog of eel calcitonin. Elcatonin increases bone mineral density, inhibits bone resorption and processes a central analgesic effect .
loading...
    loading...
Cat. No.: HY-P10519A
Research Areas:  

Infection

Brevicidine TFA is an antimicrobial peptide with selective bactericidal activity against Gram-negative pathogens. Brevicidine TFA disrupts bacterial morphology by binding to lipopolysaccharide (LPS) on the bacterial cell membrane to form pores. Brevicidine TFA causes dissipation of intracellular proton motive force, outer membrane damage, inhibition of ATP biosynthesis and reactive oxygen species accumulation in bacterial cells. As a sensitizer, Brevicidine TFA exerts synergistic activity when combined with a variety of conventional antibiotics .
loading...
    loading...