Elcatonin
Elcatonin (Carbocalcitonin) is a synthetic analog of eel calcitonin. Elcatonin increases bone mineral density, inhibits bone resorption and processes a central analgesic effect.
For research use only. We do not sell to patients.
- CAS No.: 60731-46-6
- Formula: C148H244N42O47
- Molecular Weight:3363.77
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Sprague-Dawley rats weighing 150-250 g (Oxaliplatin-Induced Allodynia Models)[1]
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Dosage:20 U/kg
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Administration:Subcutaneously; 2 d after oxaliplatin administration
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Result:Attenuated oxaliplatin-induced cold in rtas.
Chemical Information
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CAS No. 60731-46-6
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Molecular Weight 3363.77
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Formula C148H244N42O47
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Synonyms
Carbocalcitonin
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Sequence
Ser-Asn-Leu-Ser-Thr-Asu-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Gly-Thr-Pro-NH2 (Lactam bridge: Ser1-Asu6)
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Sequence Shortening
SNLST{Asu}VLGKLSQELHKLQTYPRTDVGAGTP-NH2 (Lactam bridge: Ser1-Asu6)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Knopp JA, et al. Calcitonin for treating acute pain of osteoporotic vertebral compression fractures: a systematic review of randomized, controlled trials. Osteoporos Int. 2005;16(10):1281‐1290. [Content Brief]
[2]. Aoki M,et al. Comparison of the effects of single doses of elcatonin and pregabalin on oxaliplatin-induced cold and mechanical allodynia in rats. Biol Pharm Bull. 2014;37(2):322‐326. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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