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Results for "

Shp2-PTP

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

2

Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W099617
    2,3-Dihydroxypropyl decanoate

    1-Decanoyl-rac-glycerol

    		 Biochemical Assay Reagents Drug Derivative Others
    2,3-Dihydroxypropyl decanoate (1-Decanoyl-rac-glycerol) is a derivative of Decanoic acid (HY-W015309) and a non-ionic surfactant, with an IC50 > 100 μM against Shp2-PTP, VHR and HePTP. 2,3-Dihydroxypropyl decanoate is found in the roots of Angelica dahurica (Baizhi). 2,3-Dihydroxypropyl decanoate acts as a component of reverse micelle systems for the encapsulation of proteins and nucleic acids [2] .
    2,3-Dihydroxypropyl decanoate
  • HY-112478
    PTP Inhibitor IV

    		Phosphatase SHP2 Cancer
    PTP Inhibitor IV is a protein tyrosine phosphatase (PTP) inhibitor that competitively inhibits DUSP14 phosphatase activity with an 50 of 5.21 μM . PTP Inhibitor IV inhibits SHP-2, PTP1B, PTP-ε, PTP Meg-2, PTP-σ, PTP-β, and PTP-μ with 50s of 1.8 μM, 2.5 μM, 8.4 μM, 13 μM, 20 μM, 6.4 μM, and 6.7 μM, respectively [2].
    PTP Inhibitor IV
  • HY-162755
    SHP2-IN-30

    		SHP2 Apoptosis Cancer
    SHP2-IN-30 (compound 14i) is an allosteric SHP2 inhibitor with an IC50 of 104 nM. SHP2-IN-30 shows low inhibitory effect on SHP2-PTP. SHP2-IN-30 induces cell apoptosis and arrests the cell cycle at the G0/G1 phase .
    SHP2-IN-30
  • HY-181239
    PTP1B-IN-33

    		Phosphatase Inflammation/Immunology Cancer
    PTP1B-IN-33 is a PTP1B inhibitor with a human IC50 of 2.45 μM and over 20-fold selectivity for PTP1B over SHP2. PTP1B-IN-33 enhances π-Alkyl interaction with PTP1B to increase WPD loop closure degree. PTP1B-IN-33 can be used for the research of cancer, diabetes, autoimmune deficiency diseases .
    PTP1B-IN-33

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