12 Results for "

Sodium cholate

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "Sodium cholate" in MCE Product Catalog:

21
21 Cited Publications
Cat. No.: HY-N0324A
CAS No.: 361-09-1
Synonyms: Sodium cholate
Cholic acid sodium is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid sodium is orally active .
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Cat. No.: HY-107830
CAS No.: 1448-36-8
Purity:  99.81%
Methyl cholate is a bile acid analog and a specific inhibitor of TcdB toxin from Clostridioides difficile. Methyl cholate exerts a stronger selective inhibitory effect on TcdB than on TcdA. Methyl cholate induces conformational stabilization by binding to a unique site of TcdB, thereby blocking the binding of the toxin to host receptors and its self-processing process. Methyl cholate effectively protects human fibroblasts from TcdB-induced cytopathic effects. Methyl cholate exhibits dose-dependent anti-hepatic fibrosis activity in both cellular and zebrafish models, and significantly reduces the expression levels of α-SMA and COL-I. Methyl cholate is suitable for in-depth research in the fields of Clostridioides difficile infection and hepatic fibrosis .
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Cat. No.: HY-E70073
CAS No.: 2170331-76-5
Synonyms: Sialidase isoenzyme M2; AuSialidase M2
Research Areas:  

Others

Ganglioside sialidase (AuSialidase M2) from Arthrobacter ureafaciens. Ganglioside sialidase is a highly specific N-acetylneuraminidase. Ganglioside sialidase can hydrolyze the internal sialic acid of GM1 under optimal condition with sodium cholate .
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Cat. No.: HY-107830R
CAS No.: 1448-36-8
Methyl cholate (Standard) is the analytical standard of Methyl cholate. This product is intended for research and analytical applications. Methyl cholate is a bile acid analog and a specific inhibitor of TcdB toxin from Clostridioides difficile. Methyl cholate exerts a stronger selective inhibitory effect on TcdB than on TcdA. Methyl cholate induces conformational stabilization by binding to a unique site of TcdB, thereby blocking the binding of the toxin to host receptors and its self-processing process. Methyl cholate effectively protects human fibroblasts from TcdB-induced cytopathic effects. Methyl cholate exhibits dose-dependent anti-hepatic fibrosis activity in both cellular and zebrafish models, and significantly reduces the expression levels of α-SMA and COL-I. Methyl cholate is suitable for in-depth research in the fields of Clostridioides difficile infection and hepatic fibrosis .
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Cat. No.: HY-W746556
CAS No.: 52886-39-2
Methyl cholate-d5 is the deuterium labeled Methyl cholate. Methyl cholate is a bile acid analog and a specific inhibitor of TcdB toxin from Clostridioides difficile. Methyl cholate exerts a stronger selective inhibitory effect on TcdB than on TcdA. Methyl cholate induces conformational stabilization by binding to a unique site of TcdB, thereby blocking the binding of the toxin to host receptors and its self-processing process. Methyl cholate effectively protects human fibroblasts from TcdB-induced cytopathic effects. Methyl cholate exhibits dose-dependent anti-hepatic fibrosis activity in both cellular and zebrafish models, and significantly reduces the expression levels of α-SMA and COL-I. Methyl cholate is suitable for in-depth research in the fields of Clostridioides difficile infection and hepatic fibrosis .
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Cat. No.: HY-W155121
CAS No.: 86303-22-2
Synonyms: N,N-Bis(3-D-gluconamidopropyl)cholamide
Big CHAP are aqueous micelles of anionic cholate analogues .
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Cat. No.: HY-N0324AR
CAS No.: 361-09-1
Synonyms: Sodium cholate (Standard)
Cholic acid (sodium) (Standard) is the analytical standard of Cholic acid (sodium). This product is intended for research and analytical applications. Cholic acid sodium is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid sodium is orally active[1][2].
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Cat. No.: HY-E72011
Research Areas:  

Others

7α-Hydroxysteroid dehydrogenase (EC 1.1.1.159) is an oxidoreductase that can convert cholate and NAD + into 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate, NADH and H +.
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Cat. No.: HY-E71654
Research Areas:  

Others

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]Propanoate-CoA ligase (EC 6.2.1.41) catalyses a step in the degradation of cholesterol and cholate.
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Cat. No.: HY-P83671
Synonyms: cholate, cholanic acid,cholalin, colalin, cholalic acid, 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanicacid, cholsaeure

Host:  

Mouse

Application:  

ELISA

Reactivity:  

Species independent

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Cat. No.: HY-E71945
Research Areas:  

Others

5β-Cholestane-3α,7α-diol 12α-hydroxylase (EC 1.14.13.96) is an oxidoreductase that can catalyze multiple reactions, including reaction 1: convert 5beta-cholestane-3alpha,7alpha-diol, reduced [NADPH--hemoprotein reductase] and O2 into 5beta-cholestane-3alpha,7alpha,12alpha-triol, oxidized [NADPH--hemoprotein reductase], H2O and H +; reaction 2: convert 7alpha-hydroxycholest-4-en-3-one, reduced [NADPH--hemoprotein reductase] and O2 into 7alpha,12alpha-dihydroxycholest-4-en-3-one, oxidized [NADPH--hemoprotein reductase], H2O and H +; reaction 3: convert chenodeoxycholate, reduced [NADPH--hemoprotein reductase] and O2 into cholate, oxidized [NADPH--hemoprotein reductase], H2O and H +.
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Cat. No.: HY-E72010
Research Areas:  

Others

7α-Hydroxycholest-4-en-3-one 12α-hydroxylase (EC 1.14.18.8) is an oxidoreductase that can catalyze multiple reactions, including reaction 1: convert 5beta-cholestane-3alpha,7alpha-diol, reduced [NADPH--hemoprotein reductase] and O2 into 5beta-cholestane-3alpha,7alpha,12alpha-triol, oxidized [NADPH--hemoprotein reductase], H2O and H +; reaction 2: convert 7alpha-hydroxycholest-4-en-3-one, reduced [NADPH--hemoprotein reductase] and O2 into 7alpha,12alpha-dihydroxycholest-4-en-3-one, oxidized [NADPH--hemoprotein reductase], H2O and H +; reaction 3: convert chenodeoxycholate, reduced [NADPH--hemoprotein reductase] and O2 into cholate, oxidized [NADPH--hemoprotein reductase], H2O and H +.
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