6 Results for "

T-REx-293

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "T-REx-293" in MCE Product Catalog:

Cat. No.: HY-P10221A
Research Areas:  

Cancer

Cyclo(CKLIIF) TFA is an inhibitor of HIF-1α and HIF-2α. The KD values of Cyclo(CKLIIF) TFA for the PAS-B domains of HIF1-α and HIF2-α are 2.6 μM and 2.2 μM, respectively. Cyclo(CKLIIF) TFA disrupts the protein-protein interaction between HIF-1α and HIF-1β. Cyclo(CKLIIF) TFA can be used in cancer research .
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Cat. No.: HY-P10222
Research Areas:  

Cancer

Cyclo CRLLIF is a dual inhibitor for hypoxia inducible factor (HIF) 1 and 2, which disrupts the interaction of both HIF1-α and HIF2-α with HIF1-β, with affinity for HIF1-α and HIF2-α PAS-B domains KD of 14.5 and 10.2 μM, respectively .
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Cat. No.: HY-P10223
Research Areas:  

Cancer

Cyclo CRVIIF is a dual inhibitor for hypoxia inducible factor (HIF) 1 and 2, which disrupts the interaction of both HIF1-α and HIF2-α with HIF1-β, with affinity for HIF1-α and HIF2-α PAS-B domains KD of 65 and 123 μM, respectively .
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Cat. No.: HY-184953
CAS No.: 3099598-25-8
Research Areas:  

Cancer

Anticancer agent 345 is a heterobifunctional anticancer compound that exhibits weak antiproliferative activity against both ERα-overexpressing and non-overexpressing T-Rex 293 cells . Anticancer agent 345 can be used in cancer-related research .
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Cat. No.: HY-184960
CAS No.: 3099599-58-0
Research Areas:  

Cancer

Anticancer agent 352 is a heterobifunctional anticancer compound. Anticancer agent 352 exhibits only weak antiproliferative activity against both ERα-overexpressing and non-overexpressing T-Rex 293 cells induced by Doxorubicin (HY-15142A). Anticancer agent 352 can be used in breast cancer-related research .
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Cat. No.: HY-184900
CAS No.: 3099598-43-0
Target:  

Estrogen Receptor/ERR

Research Areas:  

Cancer

Anticancer agent 341 (Compound III-163) is a non-ERα-dependent cytotoxic agent with its GI50 for MCF cells is 0.05-0.5 μΜ. Anticancer agent 341 exhibits GI50 for T-Rex 293 cells regardless of whether Doxycycline (Dox) (HY-N0565) is added of all < 0.05 μΜ. Anticancer agent 341 can be used in breast cancer research .
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