Anticancer agent 345
Anticancer agent 345 is a heterobifunctional anticancer compound that exhibits weak antiproliferative activity against both ERα-overexpressing and non-overexpressing T-Rex 293 cells. Anticancer agent 345 can be used in cancer-related research.
For research use only. We do not sell to patients.
- CAS No.: 3099598-25-8
- Formula: C54H57N7O3S
- Molecular Weight:884.14
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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ERα |
Anticancer agent 345 (III-154) exhibits moderate antiproliferative activity against MCF7 cells (GI50 = 0.0-0.5 μM)[1].
Anticancer agent 345 exhibits weak antiproliferative activity against both estrogen receptor α-overexpressing and non-overexpressing T-Rex 293 cells induced by Doxorubicin (HY-15142A) (GI50 > 2.5 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3099598-25-8
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Molecular Weight 884.14
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Formula C54H57N7O3S
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SMILES
CC1=C(C)SC2=C1C(C3=CC=C(N4CCC(O)(CC4)CC5CCN(C6=CC=C([C@@H]7C8=CC=C(O)C=C8CC[C@@H]7C9=CC=CC=C9)C=C6)CC5)C=C3)=N[C@H](CC%10=NC=CO%10)C%11=NN=C(C)N2%11
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)