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Results for "

TRM

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Histamine Receptor (1) JAK (1) RNA MTase (1) STAT (1) Transmembrane Glycoprotein (1)
By Research Areas:	Cancer (1) Infection (1) Inflammation/Immunology (1) Metabolic Disease (1)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P990127

Anti-Mouse CD80/B7-1 Antibody (RM80)	Transmembrane Glycoprotein	Inflammation/Immunology
Anti-Mouse CD80/B7-1 Antibody (RM80) is an anti-mouse CD80/B7-1 IgG2a monoclonal antibody. Anti-Mouse CD80/B7-1 Antibody (RM80) can inhibit the number of tissue-resident memory (T_RM) cells. Anti-Mouse CD80/B7-1 Antibody (RM80) can prolong the survival time of transplants combined with CD86 mAb. Anti-Mouse CD80/B7-1 Antibody (RM80) can be used for researches on inflammation conditions and immunology such as viral myocarditis and corneal transplant .

HY-170393

iBFAR2	JAK STAT	Cancer
iBFAR2, a BFAR inhibitor, restores the CD8+ TRM cell subset against solid tumors. iBFAR2 promotes JAK2-STAT1 association and STAT1 phosphorylation .

HY-19179

TRM-115	Histamine Receptor	Metabolic Disease
TRM-115 is a histamine H2 receptor antagonist. TRM-115 is promising for research of digestive system disease .

HY-180544

TrmD-IN-1	RNA MTase	Infection
TrmD-IN-1 (compound 8h) is a selective Staphylococcus aureus tRNA m1 G37 methyltransferase (TrmD) inhibitor with a K_D of 2.48 μM and an IC₅₀ of 1.16 μM. TrmD-IN-1 exhibits selectivity over E. coli (K_D > 30 μM) and H. influenzae TrmD (K_D > 30 μM) and *Trm5* (IC₅₀ > 30 μM) .

Cat. No.	Product Name	Target	Research Area	Image

HY-P990127

Anti-Mouse CD80/B7-1 Antibody (RM80)	Transmembrane Glycoprotein	Inflammation/Immunology
Anti-Mouse CD80/B7-1 Antibody (RM80) is an anti-mouse CD80/B7-1 IgG2a monoclonal antibody. Anti-Mouse CD80/B7-1 Antibody (RM80) can inhibit the number of tissue-resident memory (T_RM) cells. Anti-Mouse CD80/B7-1 Antibody (RM80) can prolong the survival time of transplants combined with CD86 mAb. Anti-Mouse CD80/B7-1 Antibody (RM80) can be used for researches on inflammation conditions and immunology such as viral myocarditis and corneal transplant .

Species:	Human (2)
Tag:	SUMO (1) His (2)
Source:	E. coli (2)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P71644

	TRMT112 Protein, Human (His-SUMO) TRMT112; AD-001; HSPC152; HSPC170; Multifunctional methyltransferase subunit TRM112-like protein; tRNA methyltransferase 112 homolog	Human	E. coli
	TRMT112 protein activates various methyltransferases for rRNA, tRNA, and protein modifications. It cooperates with BUD23 to methylate guanine N(7) of 18S rRNA. TRMT112 Protein, Human (His-SUMO) is the recombinant human-derived TRMT112 protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

HY-P703465

	KMT9a/KMT9b Protein, Human (His) Multifunctional methyltransferase subunit TRM112-like protein; tRNA methyltransferase 112 homolog; TRMT112; Homo sapiens; Human	Human	E. coli
	TRMT112 protein activates various methyltransferases for rRNA, tRNA, and protein modifications. It cooperates with BUD23 to methylate guanine N(7) of 18S rRNA. KMT9a/KMT9b Protein, Human (His) is the recombinant human-derived KMT9a/KMT9b, expressed by E. coli, with His labeled tag.

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Host:	Mouse (5) Rabbit (1)
Reactivity:	Human (5) human (1)
Application:	IHC-P (5) ICC/IF (1) IP (1) WB (2) FC (1)
Isotype:	IgG (1) IgG1 (1) IgG2a (2) IgG2b (2)
Conjugation:	Non-conjugated (6)
Clonality:	Monoclonal (3) Recombinant (1)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P810198

	TRM61 Antibody (YA9542)	WB, IP	human
	TRM61 Antibody (YA9542) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TRM61.

HY-P88633

	TRMT12 Antibody (YA8317) TRM12; TYW2	IHC-P	Human
	TRMT12 Antibody (YA8317) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to TRMT12.

HY-P88610

	TRMT5 Antibody (YA8294) COXPD26; KIAA1393; TRM5	IHC-P	Human
	TRMT5 Antibody (YA8294) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to TRMT5.

HY-P88633A

	TRMT12 Antibody (YA8317)(PBS only) TRM12; TYW2	IHC-P	Human
	TRMT12 Antibody (YA8317) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to TRMT12.

HY-P88610A

	TRMT5 Antibody (YA8294)(PBS only) COXPD26; KIAA1393; TRM5	IHC-P	Human
	TRMT5 Antibody (YA8294) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to TRMT5.

HY-P83179

	WDR4 Antibody (YA2924) TRM82; WD repeat protein 4; wdr4	WB, IHC-P, ICC/IF, FC	Human
	WDR4 Antibody (YA2924) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to WDR4.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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