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Results for "

VKOR

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Recombinant Proteins

1

Isotope-Labeled Compounds

1

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-14854
    Tecarfarin

    ATI-5923

    		 VKOR Cardiovascular Disease
    Tecarfarin (ATI-5923) is an orally active and non-competitive vitamin K epoxide reductase (VKOR) antagonist, and impairs the activation of the vitamin K-dependent clotting factors II, VII, IX and X . Tecarfarin has the antithrombotic activity .
    Tecarfarin
  • HY-RS15659
    VKORC1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    VKORC1 Human Pre-designed siRNA Set A contains three designed siRNAs for VKORC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    VKORC1 Human Pre-designed siRNA Set A
    VKORC1 Human Pre-designed siRNA Set A
  • HY-134999
    10-Hydroxywarfarin

    		Drug Metabolite Cytochrome P450 VKOR Metabolic Disease
    10-Hydroxywarfarin, a metabolite of (R)-(+)-Warfarin (HY-W015998 ), is a CYP2C9 and vitamin K epoxide reductase complex 1 (VKOR) inhibitor with IC50s of 1.6 µM and 80 ng/mL, respectively .
    10-Hydroxywarfarin
  • HY-14854A
    Tecarfarin sodium

    ATI-5923 sodium

    		 VKOR Cardiovascular Disease
    Tecarfarin (ATI-5923) sodium is an orally active VKOR inhibitor with an IC50 of 0.67 μM against VKORC1. Tecarfarin sodium blocks the post-translational modification of vitamin K-dependent coagulation factors II, VII, IX and X, reducing their levels and activities. Tecarfarin sodium prolongs prothrombin time, attenuates venous and arterial thrombosis, increases ear incision bleeding volume, and exerts reversible anticoagulant effects. Tecarfarin sodium is applicable to research related to arterial and venous thrombosis as well as other diseases requiring anticoagulation .
    Tecarfarin sodium
  • HY-14854R
    Tecarfarin (Standard)

    ATI-5923 (Standard)

    		 Reference Standards VKOR Cardiovascular Disease
    Tecarfarin (ATI-5923) (Standard) is the analytical standard of Tecarfarin. This product is intended for research and analytical applications. Tecarfarin is an orally active VKOR inhibitor with an IC50 of 0.67 μM against VKORC1. Tecarfarin blocks the post-translational modification of vitamin K-dependent coagulation factors II, VII, IX and X, reducing their levels and activities. Tecarfarin prolongs prothrombin time, attenuates venous and arterial thrombosis, increases ear incision bleeding volume, and exerts reversible anticoagulant effects. Tecarfarin is applicable to research related to arterial and venous thrombosis as well as other diseases requiring anticoagulation .
    Tecarfarin (Standard)
  • HY-14854S
    Tecarfarin-13C,d3

    ATI-5923-13C,d3

    		 Isotope-Labeled Compounds VKOR Cardiovascular Disease
    Tecarfarin- 13C,d3 (ATI-5923- 13C,d3) is 13C labeled Tecarfarin. Tecarfarin is an orally active VKOR inhibitor with an IC50 of 0.67 μM against VKORC1. Tecarfarin blocks the post-translational modification of vitamin K-dependent coagulation factors II, VII, IX and X, reducing their levels and activities. Tecarfarin prolongs prothrombin time, attenuates venous and arterial thrombosis, increases ear incision bleeding volume, and exerts reversible anticoagulant effects. Tecarfarin is applicable to research related to arterial and venous thrombosis as well as other diseases requiring anticoagulation .
    Tecarfarin-13C,d3

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