Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
WD repeat-containing protein 5
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "WD repeat-containing protein 5" in MCE Product Catalog:
5
5 Cited Publications
WDR5-IN-4 TFA (Compound C6) is an inhibitor of the WIN site of chromatin-associated WD repeat-containing protein 5 (WDR5), with a Kd of 0.1 nM. WDR5-IN-4 TFA displaces WDR5 from chromatin and decreases the expression of associated genes, causing translational inhibition, nucleolar stress. Anti-cancer activity .
2
Target:
Research Areas:
WDR5-0103 (WD-Repeat Protein 5-0103) is a potent and selective WD repeat-containing protein 5 (WDR5) antagonist with a Kd of 450 nM. WDR5-0103 competitively binds to the peptide-binding pocket of WDR5, blocking the interaction between WDR5 and mixed-lineage leukemia (MLL) protein and inhibiting the methyltransferase activity of MLL. WDR5-0103 is mainly used in the research of cancer and neurodegenerative diseases .
Cat. No.: HY-111753AR
CAS No.: 2749300-35-2
Target:
Research Areas:
WDR5-IN-4 TFA (Standard) is the analytical standard of WDR5-IN-4 (TFA) (HY-111753A). This product is intended for research and analytical applications. WDR5-IN-4 TFA (Compound C6) is an inhibitor of the WIN site of chromatin-associated WD repeat-containing protein 5 (WDR5), with a Kd of 0.1 nM. WDR5-IN-4 TFA displaces WDR5 from chromatin and decreases the expression of associated genes, causing translational inhibition, nucleolar stress. Anti-cancer activity .
Cat. No.: HY-P703615
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: WDR5; WD repeat Domain 5; CFAP89; BIG‑3; SWD3; Cilia And Flagella Associated protein 89; WD repeat‑containing protein 5; BMP2‑Induced 3‑Kb Gene protein; BMP‑2‑Induced Gene 3 Kb; BIG3; SWD3, Set1c WD40 repeat protein, Homolog (S. Cerevisiae); SWD3, Set1c W
Cat. No.: HY-P702880
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: WDR5; WD repeat Domain 5; CFAP89; BIG‑3; SWD3; Cilia And Flagella Associated protein 89; WD repeat‑containing protein 5; BMP2‑Induced 3‑Kb Gene protein; BMP‑2‑Induced Gene 3 Kb; BIG3; SWD3, Set1c WD40 repeat protein, Homolog (S. Cerevisiae); SWD3, Set1c W
Species:
Source:
Cat. No.: HY-P702881
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: WDR5; WD repeat Domain 5; CFAP89; BIG‑3; SWD3; Cilia And Flagella Associated protein 89; WD repeat‑containing protein 5; BMP2‑Induced 3‑Kb Gene protein; BMP‑2‑Induced Gene 3 Kb; BIG3; SWD3, Set1c WD40 repeat protein, Homolog (S. Cerevisiae); SWD3, Set1c W
Species:
Source:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
