WDR5 Antibody (YA5099)
(Synonyms: WDR5; BIG3; WD repeat-containing protein 5; BMP2-induced 3-kb gene protein)Based on 1 Customer Validation
WDR5 Antibody (YA5099) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to WDR5.
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Host:
Rabbit
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Isotype:
IgG
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Application:
IHC-P, IHC-F, FC, IF-Tissue
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Reactivity :
Human, Rat
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Formulation:
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IHC-F
IHC-F: Immunohistochemistry-Frozen
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FC
FC: Flow Cytometry
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IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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|---|---|---|---|---|
| Dilution Ratio | 1:100-500 | 1:100-500 | 1:50-100 | 1:100-500 |
Product Details
WDR5 Antibody (YA5099) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to WDR5.
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Host Rabbit
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Clonality Monoclonal,Recombinant
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Species ReactivityHuman, Rat
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Observed Molecular WeightObserved band size: 36 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 37 kDa
A synthesized peptide derived from human WDR5. The exact sequence is proprietary to MCE.
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% glycerol.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
WDR5 is a highly conserved WD40 repeat-containing protein that is essential for proper regulation of multiple cellular processes. WDR5 is best characterized as a core scaffolding component of histone methyltransferase complexes. WDR5 also plays a crucial role in mediating protein-protein interactions that sustain oncogenesis in human cancers. One prominent example is the interaction between the transcription factor MYC and WDR5, which is essential for oncogenic processes.
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Subcellular Localization
Nucleus
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Subunit
Interacts with HCFC1 (PubMed:12670868). Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (PubMed:19103755).
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SwissProt ID
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Synonyms
WDR5; BIG3; WD repeat-containing protein 5; BMP2-induced 3-kb gene protein
Documentation
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