9 Results for "

WDR5-MLL

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "WDR5-MLL" in MCE Product Catalog:

4
MM-102 TFA
MM-102 TFA
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4 Cited Publications
Cat. No.: HY-12220A
CAS No.: 1883545-52-5
Purity:  99.68%
Synonyms: HMTase Inhibitor IX TFA
Target:  

WDR5

Research Areas:  

Cancer

MM-102 TFA (HMTase Inhibitor IX TFA) is a potent WDR5/MLL interaction inhibitor, achieves IC50 = 2.4 nM with an estimated Ki < 1 nM in WDR5 binding assay, which is >200 times more potent than the ARA peptide.
OICR-0547
OICR-0547
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Cat. No.: HY-16994
CAS No.: 1801873-49-3
Target:  

WDR5

Research Areas:  

Cancer

OICR-0547 is a negative control, closely related derivative of OICR-9429 (HY-16993). OICR-9429 is a novel small-molecule antagonist of the Wdr5-MLL interaction. OICR-0547 is an inactive control compound that no longer binds to WDR5 .
DDO-2213
DDO-2213
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Cat. No.: HY-153331
CAS No.: 2378768-36-4
Target:  

WDR5

Research Areas:  

Cancer

DDO-2213 is an orally active and potent WDR5-MLL1 inhibitor, with an IC50 of 29 nM and a Kd value of 72.9 nM for the WDR5 protein. DDO-2213 selectively inhibits MLL (mixed lineage leukemia) histone methyltransferase activity and the proliferation of MLL translocation-harboring cells. DDO-2213 can be used for MLL fusion leukemia research .
WDR5-47
WDR5-47
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Cat. No.: HY-157659
CAS No.: 1422389-91-0
Target:  

WDR5

Research Areas:  

Others

WDR5-MLL1 antagonist 1 (compound 47) is a compound optimized through protein crystal structure guidance. It has stronger antagonistic activity against WDR5-MLL interaction with a dissociation constant (Kd) of 0.3μM.
WDR5-0102
WDR5-0102
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Cat. No.: HY-148817
CAS No.: 824960-50-1
Purity:  97.02%
Target:  

WDR5

Research Areas:  

Cancer

WDR5-0102 is an inhibitor of WDR5. WDR5-0102 specifically targets the WIN site of WDR5, disrupts the WDR5-MLL1 interaction, and reduces the histone methyltransferase activity of MLL1. WDR5-0102 exerts dose-dependent toxicity on MDSC-like cells and reduces their osteopontin levels, while showing extremely low cytotoxicity to pancreatic cancer cells. WDR5-0102 can be used in the research of related diseases such as acute myeloid leukemia, lymphoid leukemia, biphenotypic leukemia and pancreatic cancer .
Z116334910
Z116334910
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Cat. No.: HY-178751
CAS No.: 412940-42-2
Target:  

WDR5

Research Areas:  

Cancer

Z116334910 is a promising WDR5-MLL1 interaction disruptor. Z116334910 can be used for the study of cancer .
Z88418521
Z88418521
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Cat. No.: HY-178752
CAS No.: 1240704-07-7
Target:  

WDR5

Research Areas:  

Cancer

Z88418521 is a ligand for the WDR5-MLL1 complex. Z88418521 may help disrupt the interaction of the WDR5-MLL1 complex. Z88418521 can be used in cancer research, especially in leukemia .
DD0-2363
DD0-2363
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Cat. No.: HY-168475
Target:  

Apoptosis WDR5 HDAC

Research Areas:  

Cancer

DD0-2363 (Compound 32d) is a dual-target inhibitor of WDR5-MLL1/HDAC. DD0-2363 inhibits cells proliferation and induces apoptosis in acute myeloid leukemia cells. DD0-2363 has antitumor activity and can be used in the research of acute myeloid leukemia .
DC_M5_2
DC_M5_2
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Cat. No.: HY-183959
CAS No.: 713099-37-7
Target:  

WDR5

Research Areas:  

Cancer

DC_M5_2 is a WD40 repeat domain protein 5 (WDR5) inhibitor with an IC50 of 9.63 μM and a KD of 13.8 μM. DC_M5_2 binds to the WDR5 pocket that interacts with the MLL1 peptide, blocking the WDR5-MLL1 protein-protein interaction . DC_M5_2 can be used in leukemia-related research .
Assay Types