WDR5-47
Based on 1 Customer Validation
WDR5-MLL1 antagonist 1 (compound 47) is a compound optimized through protein crystal structure guidance. It has stronger antagonistic activity against WDR5-MLL interaction with a dissociation constant (Kd) of 0.3μM.
For research use only. We do not sell to patients.
- Purity: 98.34%
- CAS No.: 1422389-91-0
- Formula: C19H20ClFN4O3
- Molecular Weight:406.84
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 1422389-91-0
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Appearance Solid
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Molecular Weight 406.84
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Formula C19H20ClFN4O3
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Color Light yellow to yellow
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SMILES
O=C(NC1=CC([N+]([O-])=O)=CC=C1N2CCN(C)CC2)C3=CC=C(F)C(C)=C3Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 20.83 mg/mL (51.20 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4580 mL | 12.2898 mL | 24.5797 mL | 61.4492 mL |
| 5 mM | 0.4916 mL | 2.4580 mL | 4.9159 mL | 12.2898 mL | |
| 10 mM | 0.2458 mL | 1.2290 mL | 2.4580 mL | 6.1449 mL | |
| 15 mM | 0.1639 mL | 0.8193 mL | 1.6386 mL | 4.0966 mL | |
| 20 mM | 0.1229 mL | 0.6145 mL | 1.2290 mL | 3.0725 mL | |
| 25 mM | 0.0983 mL | 0.4916 mL | 0.9832 mL | 2.4580 mL | |
| 30 mM | 0.0819 mL | 0.4097 mL | 0.8193 mL | 2.0483 mL | |
| 40 mM | 0.0614 mL | 0.3072 mL | 0.6145 mL | 1.5362 mL | |
| 50 mM | 0.0492 mL | 0.2458 mL | 0.4916 mL | 1.2290 mL |
WDR5-47 Related Classifications
HY-157659 Related Classifications
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