5 Results for "

alpha-KTx

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "alpha-KTx" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P1280
CAS No.: 145808-47-5
Margatoxin, an alpha-KTx scorpion toxin, is a high affinity inhibitor of Kv1.3 (Kd=11.7 pM). Margatoxin inhibits the Kv1.2 (Kd=6.4 pM) and Kv1.1 (Kd=4.2 nM). Margatoxin, a 39 amino-acid-long peptide, is isolated from the venom of the scorpion Centruroides margaritatus and widely used in ion channel research .
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Cat. No.: HY-P5931
CAS No.: 752984-66-0
Synonyms: Potassium channel toxin alpha-KTx 6.13; SPX; α-KTx6.13
Target:  

Potassium Channel

Research Areas:  

Inflammation/Immunology Cancer

Spinoxin isolated from the venom of scorpion Heterometrus spinifer, is a 34-residue peptide neurotoxin cross-linked by four disulfide bridges. Spinoxin is a potent inhibitor of Kv1.3 potassium channel (IC50 = 63 nM), considering to be valid molecular targets in the diagnostics and therapy of various autoimmune disorders and cancers .
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Cat. No.: HY-P1280A
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

Margatoxin TFA, an alpha-KTx scorpion toxin, is a high affinity inhibitor of Kv1.3 (Kd=11.7 pM). Margatoxin TFA inhibits the Kv1.2 (Kd=6.4 pM) and Kv1.1 (Kd=4.2 nM). Margatoxin TFA, a 39 amino-acid-long peptide, is isolated from the venom of the scorpion Centruroides margaritatus and widely used in ion channel research .
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Cat. No.: HY-P5920
Synonyms: α-KTx 6.21
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

Urotoxin is an inhibitor of the potassium channel. Urotoxin has a selective affinity for hKv1.2 channel .
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Cat. No.: HY-P3316
CAS No.: 183815-75-0
OSK-1 is a potent Kv channel blocker with IC50s of of 0.6 nM, 5.4 nM, 0.014 nM for Kv1.1, Kv1.2 and Kv1.3, respectively. OSK1 is a moderate blocker of Ca 2+-activated KCa3.1 channel with an IC50 of 225 nM. OSK-1 belongs to α-KTx3 toxins and is used as a immunosuppressive agent .
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