752984-66-0
Chemical Structure
Spinoxin
Synonym(s): Potassium channel toxin alpha-KTx 6.13; SPX; α-KTx6.13
- CAS No.: 752984-66-0
- Formula:C147H236N48O46S9
- Molecular Weight:3700.33
SMILES: O=C1N2[C@@](CCC2)(C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@]3(C(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@]4(C(=O)N[C@@H](CCCCN)C(=O)N[C@@]5(C(=O)N[C@@H](CC6=CC=C(O)C=C6)C(=O)NCC(=O)N[C@H](C(N)=O)CSSC[C@@]1(NC(=O)CNC(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCSC)NC(=O)[C@](CSSC5)(NC(=O)[C@]7(N(C(=O)[C@H](CO)NC(=O)[C@H](CC8=CC=C(O)C=C8)NC(=O)[C@](CSSC4)(NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](NC([C@@H](NC([C@H]([C@H](CC)C)N)=O)CCCNC(=N)N)=O)CSSC3)[H])CCC7)[H])[H])[H])[H])[H])[H])[H])[H])[H]
Biological Activity: Spinoxin isolated from the venom of scorpion Heterometrus spinifer, is a 34-residue peptide neurotoxin cross-linked by four disulfide bridges. Spinoxin is a potent inhibitor of Kv1.3 potassium channel (IC50 = 63 nM), considering to be valid molecular targets in the diagnostics and therapy of various autoimmune disorders and cancers[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Spinoxin | 98.0% | Spinoxin isolated from the venom of scorpion Heterometrus spinifer, is a 34-residue peptide neurotoxin cross-linked by four disulfide bridges. Spinoxin is a potent inhibitor of Kv1.3 potassium channel (IC50 = 63 nM), considering to be valid molecular targets in the diagnostics and therapy of various autoimmune disorders and cancers. | ||||||||||||||||||||
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Keywords
