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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
arginase 2
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "arginase 2" in MCE Product Catalog:
12
12 Publications Verification
Synonyms: CB-1158; INCB01158
Numidargistat (CB-1158) is a potent and orally active inhibitor of arginase, with IC50s of 86 nM and 296 nM for recombinant human arginase 1 and recombinant human arginase 2, respectively. Immuno-oncology agent .
12
12 Publications Verification
Cat. No.: HY-101979A
Purity: 98.65%
Synonyms: CB-1158 dihydrochloride; INCB01158 dihydrochloride
Numidargistat (CB-1158) dihydrochloride is a potent and orally active inhibitor of arginase, with IC50s of 86 nM and 296 nM for recombinant human arginase 1 and recombinant human arginase 2, respectively. Immuno-oncology agent .
1
1 Cited Publications
Cat. No.: HY-155108B
Purity: 99.88%
OATD-02 hydrochloride is the hydrochloride salt form of OATD-02 (HY-155108). OATD-02 hydrochloride an orally active, competitive, reversible, noncovalent dual inhibitor of Arginase1 and Arginase2. OATD-02 hydrochloride is a slow offset inhibitor, blocking intracellular arginases with IC50s of 20 nM (hARG1), 39 nM (hARG2), 39 nM (mARG1), and 28 nM (rARG1), respectively. OATD-02 hydrochloride bolishes tumor immunosuppression induced by both arginases. OATD-02 hydrochloride can be used for melanoma study .
Cat. No.: HY-P7603
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ARG2; Type II arginase; arginase 2; arginase II; arginase-2, Mitochondrial; L-Arginine Amidinohydrolase; Kidney-Type arginase; L-Arginine Ureahydrolase; Non-Hepatic arginase; Nonhepatic arginase; arginase, Type II; Kidney arginase
Cat. No.: HY-P72090
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ARG2; Type II arginase; arginase 2; arginase II; arginase-2, Mitochondrial; L-Arginine Amidinohydrolase; Kidney-Type arginase; L-Arginine Ureahydrolase; Non-Hepatic arginase; Nonhepatic arginase; arginase, Type II; Kidney arginase
Cat. No.: HY-P705455
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ARG2; Type II arginase; arginase 2; arginase II; arginase-2, Mitochondrial; L-Arginine Amidinohydrolase; Kidney-Type arginase; L-Arginine Ureahydrolase; Non-Hepatic arginase; Nonhepatic arginase; arginase, Type II; Kidney arginase
Cat. No.: HY-101979R
CAS No.: 2095732-06-0
Synonyms: CB-1158 (Standard); INCB01158 (Standard)
Target:
Research Areas:
Numidargistat (Standard) is the analytical standard of Numidargistat (HY-101979). This product is intended for research and analytical applications. Numidargistat (CB-1158) is a potent and orally active inhibitor of arginase, with IC50s of 86 nM and 296 nM for recombinant human arginase 1 and recombinant human arginase 2, respectively. Immuno-oncology agent .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
