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Results for "

calstabin1

" in MedChemExpress (MCE) Product Catalog:

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Inhibitors & Agonists

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Recombinant Proteins

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  • HY-P76346
    FKBP12 Protein, Mouse (His)

    Peptidyl-prolyl cis-trans isomerase FKBP1A; FKBP-12; calstabin-1; FKBP-1A; FKBP1

    		 Mouse E. coli
    The FKBP12 protein is multifunctional and critical in TGF-β signaling by maintaining TGFBR1 in an inactive conformation, thereby preventing receptor activation in the absence of ligand. It recruits SMAD7 to ACVR1B, blocks the binding of SMAD2 and SMAD3 to the activin receptor complex, and thereby inhibits activin signaling. FKBP12 Protein, Mouse (His) is the recombinant mouse-derived FKBP12 protein, expressed by E. coli , with N-His labeled tag.
  • HY-P76345A
    FKBP12 Protein, Human (His)

    Peptidyl-prolyl cis-trans isomerase FKBP1A; FKBP-12; calstabin-1; FKBP-1A; FKBP1

    		 Human E. coli
  • HY-P76345
    FKBP12 Protein, Human (His, solution)

    Peptidyl-prolyl cis-trans isomerase FKBP1A; FKBP-12; calstabin-1; FKBP-1A; FKBP1

    		 Human E. coli
    FKBP12 protein maintains TGFBR1 in an inactive state, inhibits activin signaling by recruiting SMAD7, and modulates RYR1 calcium channel activity. As a PPIase, it speeds up protein folding. FKBP12's multifunctionality underscores its regulatory role in cellular processes, emphasizing its importance in signaling and protein folding. FKBP12 Protein, Human (His) is the recombinant human-derived FKBP12 protein, expressed by E. coli , with C-His labeled tag.

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