6 Results for "

caudatin

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "caudatin" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N1983
CAS No.: 38395-02-7
Caudatin is an orally active and brain-penetrant C-21 steroidal found in Cynanchum bungei decne with a variety of biological activities. Caudatin can inhibit cell proliferation, migration, invasion, cause cell phase arrest, induce apoptosis, autophagy, ROS prodution and loss of mitochondrial membrane potential. Caudatin activates PARP, caspase-3, -7, -9, upregulates pro-apoptotic Bad and Bax and downregulates anti-apoptotic Bcl-2 and Bcl-XL. Caudatin suppresses VEGF, FAK phosphorylation, upregulates p21, p27, DR5 protein expression, activates the p38 MAPK, JNK and PPARα/TFEB-mediated autophagy-lysosomal signaling pathways. Caudatin can be used for the research of cancer, inflammation and neurological disease, such as glioma and Alzheimer's disease .
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Cat. No.: HY-N1983R
CAS No.: 38395-02-7
Caudatin (Standard) is the analytical standard of Caudatin (HY-N1983). This product is intended for research and analytical applications. Caudatin is an orally active and brain-penetrant C-21 steroidal found in Cynanchum bungei decne with a variety of biological activities. Caudatin can inhibit cell proliferation, migration, invasion, cause cell phase arrest, induce apoptosis, autophagy, ROS prodution and loss of mitochondrial membrane potential. Caudatin activates PARP, caspase-3, -7, -9, upregulates pro-apoptotic Bad and Bax and downregulates anti-apoptotic Bcl-2 and Bcl-XL. Caudatin suppresses VEGF, FAK phosphorylation, upregulates p21, p27, DR5 protein expression, activates the p38 MAPK, JNK and PPARα/TFEB-mediated autophagy-lysosomal signaling pathways. Caudatin can be used for the research of cancer, inflammation and neurological disease, such as glioma and Alzheimer's disease .
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Cat. No.: HY-184046
CAS No.: 1084954-73-3
Caudatin-3-O-β-D-cymaropyranosyl-(1→4)-β-D-digitoxopyranoside is a naturally derived C21 steroidal glycoside that induces cytotoxicity in leukemia cells with a IC50 of 15.7 µM. Caudatin-3-O-β-D-cymaropyranosyl-(1→4)-β-D-digitoxopyranoside can be used in leukemia research .
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Cat. No.: HY-N18393
CAS No.: 88797-64-2
Caudatin 3-O-β-D-glucopyranosyl-(1→4)-β-D-oleandropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-β-D-cymaropyranoside (compound 6) is a C-21 steroidal glycoside that can be isolated from the roots of Cynanchum otophyllum and Cynanchum caudatum .
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Cat. No.: HY-N18046
CAS No.: 1326583-13-4
Otophylloside Q is a pregnane glycoside (C-21 steroidal glycoside) isolated from the roots of Cynanchum otophyllum. With caudatin (HY-N1983), an anticancer agent, as its aglycone, Otophylloside Q contains a sugar chain composed of cymarose, oleandrose and glucose units .
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