3 Results for "

classical monocytes

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "classical monocytes" in MCE Product Catalog:

4
4 Cited Publications
Art. -Nr.: HY-110247
CAS. Nr.: 433249-94-6
Reinheit:  99.67%
TRAF-STOP inhibitor 6877002 is a selective CD40-TRAF6 interaction inhibitor. TRAF-STOP inhibitor 6877002 exerts anti-atherosclerotic activity by blocking the CD40-TRAF6 signaling pathway, inhibiting classical monocyte activation, leukocyte recruitment, and macrophage activation and migration. TRAF-STOP inhibitor 6877002 reduces the phosphorylation levels of signaling intermediates in the canonical NF-κB pathway .
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Art. -Nr.: HY-P992181
Synonyms: MEDI1116; VIB-1116; HZN-1116

Target:  

Inhibitory Antibodies

Forschungsgebiete:  

Inflammation/Immunology

AMG-329 (MEDI1116) is a human immunoglobulin G1λ monoclonal antibody targeting FLT3L. AMG-329 selectively binds to FLT3L, blocks FLT3L-FLT3 interaction, neutralizes soluble and cell-bound human FLT3L activity. AMG-329 reduces circulating relative proportions of plasmacytoid dendritic cells, conventional dendritic cells, and classical monocytes. AMG-329 does not induce antibody dependent cellular cytotoxicity. AMG-329 can be used for the research of sjögren’s disease .
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Art. -Nr.: HY-110247R
CAS. Nr.: 433249-94-6
TRAF-STOP inhibitor 6877002 (Standard) is the analytical standard of TRAF-STOP inhibitor 6877002 (HY-110247). This product is intended for research and analytical applications. TRAF-STOP inhibitor 6877002 is a selective CD40-TRAF6 interaction inhibitor. TRAF-STOP inhibitor 6877002 exerts anti-atherosclerotic activity by blocKing the CD40-TRAF6 signaling pathway, inhibiting classical monocyte activation, leukocyte recruitment, and macrophage activation and migration. TRAF-STOP inhibitor 6877002 reduces the phosphorylation levels of signaling intermediates in the canonical NF-κB pathway .
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