433249-94-6
Chemical Structure
TRAF-STOP inhibitor 6877002
- CAS No.: 433249-94-6
- Formula:C17H17NO
- Molecular Weight:251.32
IUPAC Name: (E)-3-((2,5-dimethylphenyl)amino)-1-phenylprop-2-en-1-one
InChIKey: SARYOFMRLSHZFE-ZHACJKMWSA-N
SMILES: O=C(C1=CC=CC=C1)/C=C/NC2=C(C=CC(C)=C2)C
Biological Activity: TRAF-STOP inhibitor 6877002 is a selective CD40-TRAF6 interaction inhibitor. TRAF-STOP inhibitor 6877002 exerts anti-atherosclerotic activity by blocking the CD40-TRAF6 signaling pathway, inhibiting classical monocyte activation, leukocyte recruitment, and macrophage activation and migration. TRAF-STOP inhibitor 6877002 reduces the phosphorylation levels of signaling intermediates in the canonical NF-κB pathway[1].
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TRAF-STOP inhibitor 6877002 | 99.67% | TRAF-STOP inhibitor 6877002 is a selective CD40-TRAF6 interaction inhibitor. TRAF-STOP inhibitor 6877002 exerts anti-atherosclerotic activity by blocking the CD40-TRAF6 signaling pathway, inhibiting classical monocyte activation, leukocyte recruitment, and macrophage activation and migration. TRAF-STOP inhibitor 6877002 reduces the phosphorylation levels of signaling intermediates in the canonical NF-κB pathway. | ||||||||||||||||||||
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Keywords
