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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
combination index
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "combination index" in MCE Product Catalog:
Cat. No.: HY-175988
CAS No.: 2548725-57-9
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Research Areas:
DNMT/HDAC-IN-2 (Compound Y7) is a DNMT and HDAC inhibitor with IC50 values for DNMT1, HDAC1, and HDAC6 of 365, 0.2, and 8.91 nM respectively. DNMT/HDAC-IN-2 inhibits the proliferation of breast cancer cells. DNMT/HDAC-IN-2 significantly reduces tumor growth in xenografts and transgenic breast cancer mouse models. DNMT/HDAC-IN-2 can be used for the study of breast cancer .
Cat. No.: HY-175873
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AD109 is a combination of the selective norepinephrine reuptake inhibitor Atomoxetine (HY-107370) and the antimuscarinic agent Aroxybutynin (HY-B0267C). AD109 shows orally active significantly and reduces the apnea-hypopnea index .
Cat. No.: HY-168109
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Antibacterial agent 246 (compound A33) is a antibacterial agent and has minimum inhibitory concentrations (MICs) of 0.5-4 μg/mL against twenty-three Gram-positive bacteria. Antibacterial agent 246 in combination with Polymyxin E(HY-113678) E inhibits the growth of various Gram-negative bacteria with the fractional inhibitory concentration index of 0.066 .
Cat. No.: HY-184181
CAS No.: 1596337-67-5
Antimalarial agent 63 is an inhibitor of Plasmodium falciparum. Antimalarial agent 63 exhibits inhibitory activity against field isolates of Plasmodium falciparum and Plasmodium vivax. Antimalarial agent 63 shows an antagonistic interaction when used in combination with Proguanil (HY-B0806) against Plasmodium falciparum. Antimalarial agent 63 has low cytotoxicity to hepatocytes and a high selectivity index. Antimalarial agent 63 can be used in the research of malaria .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
