1596337-67-5
Chemical Structure
Antimalarial agent 63
- CAS No.: 1596337-67-5
- Formula:C24H23ClN4O2
- Molecular Weight:434.92
InChIKey: BKNSEVLLQZLNGP-UHFFFAOYSA-N
SMILES: COC1=NC2=C(C3=CC=C(C=C3N=C2C=C1)Cl)NC4=CC(CN5CCCC5)=C(C=C4)O
Biological Activity: Antimalarial agent 63 is an inhibitor of Plasmodium falciparum. Antimalarial agent 63 exhibits inhibitory activity against field isolates of Plasmodium falciparum and Plasmodium vivax. Antimalarial agent 63 shows an antagonistic interaction when used in combination with Proguanil (HY-B0806) against Plasmodium falciparum. Antimalarial agent 63 has low cytotoxicity to hepatocytes and a high selectivity index. Antimalarial agent 63 can be used in the research of malaria[1].
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Antimalarial agent 63 | Antimalarial agent 63 is an inhibitor of Plasmodium falciparum. Antimalarial agent 63 exhibits inhibitory activity against field isolates of Plasmodium falciparum and Plasmodium vivax. Antimalarial agent 63 shows an antagonistic interaction when used in combination with Proguanil (HY-B0806) against Plasmodium falciparum. Antimalarial agent 63 has low cytotoxicity to hepatocytes and a high selectivity index. Antimalarial agent 63 can be used in the research of malaria. | |||||||||||||||||||||
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Keywords
