17 Results for "

congestion

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "congestion" in MCE Product Catalog:

Referencia número: HY-P990774
No. CAS: 2768386-15-6
Synonyms: ASP-7266; TRAB-1; UPB-101

Target:  

Interleukin Related

Áreas de investigación:  

Inflammation/Immunology

Verekitug (ASP-7266; TRAB-1; UPB-101) is a human monoclonal antibody targeting the thymic stromal lymphopoietin receptor (TSLPR), with a mean half-life of approximately 20 days. At doses of Verekitug ≥100 mg, complete and sustained TSLPR-specific occupancy is achieved, and the antibody does not bind to IL-7Rα. By inhibiting TSLP-driven inflammatory responses, Verekitug blocks TSLP-induced cell proliferation and TARC expression, while reducing fractional exhaled NO levels, blood eosinophil counts, and levels of IL-5 and IgE. Verekitug significantly improves scores for nasal polyps, nasal congestion and olfactory dysfunction, with favorable safety and good tolerability; potential adverse reactions include headache, upper respiratory tract infection, sinusitis and nasopharyngitis. Verekitug is used in relevant studies on asthma, chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease .
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Referencia número: HY-B0556A
No. CAS: 522-48-5
Synonyms: Tetryzoline hydrochloride
Target:  

Adrenergic Receptor

Áreas de investigación:  

Cardiovascular Disease Endocrinology

Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline hydrochloride is widely used for the research of nasal congestion and conjunctival congestion .
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Referencia número: HY-101063
No. CAS: 142457-00-9
Pureza:  99.64%
Target:  

Histamine Receptor

Áreas de investigación:  

Inflammation/Immunology

Amthamine is a histamine receptor (H1R-H4R) agonist. Amthamine can produce liver congestion and necrosis of liver cells. Amthamine can be used to study the induction effect of H1R-H4 agonist on hepatotoxicity .
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Referencia número: HY-B1317
No. CAS: 91-85-0
Synonyms: Neohetramine
Target:  

Histamine Receptor

Áreas de investigación:  

Inflammation/Immunology

Thonzylamine is an orally active H1 histamine receptor antagonist with good antihistaminic and antianaphylactic properties. Thonzylamine can be used for the research of hypersensitivity diseases, nasal congestion, allergic conjunctivitis and other allergic diseases .
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Referencia número: HY-129508
No. CAS: 142437-67-0
Target:  

Histamine Receptor

Áreas de investigación:  

Inflammation/Immunology

Amthamine is a histamine receptor (H1R-H4R) agonist. Amthamine can produce liver congestion and necrosis of liver cells. Amthamine can be used to study the induction effect of H1R-H4 agonist on hepatotoxicity .
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Referencia número: HY-B0556
No. CAS: 84-22-0
Synonyms: Tetryzoline
Target:  

Adrenergic Receptor

Áreas de investigación:  

Cardiovascular Disease

Tetrahydrozoline (Tetryzoline), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline is widely used for the research of nasal congestion and conjunctival congestion .
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Referencia número: HY-B0556AS
No. CAS: 1246814-66-3
Synonyms: Tetryzoline-d4 hydrochloride
Tetrahydrozoline-d4 (hydrochloride) is the deuterium labeled Tetrahydrozoline hydrochloride. Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline hydrochloride is widely used for the research of nasal congestion and conjunctival congestion .
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Referencia número: HY-109034A
No. CAS: 1202269-24-6
Synonyms: AK-272; SCO-272
Áreas de investigación:  

Cardiovascular Disease

Imarikiren hydrochloride (AK-272) is an orally active, selective Renin inhibitor with an IC50 value of 2.1 nM against h-Renin. Imarikiren hydrochloride blocks the conversion of Angiotensinogen to Angiotensin I and reduces mean arterial pressure by inhibiting Angiotensin II that binds to AT1. Imarikiren hydrochloride alleviates myocardial hypertrophy and pulmonary congestion, exerting cardioprotective effects. Imarikiren hydrochloride can be used in research related to hypertension and heart failure .
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Referencia número: HY-147299
No. CAS: 177843-85-5
Synonyms: PGE-6201204
Target:  

Adrenergic Receptor

Áreas de investigación:  

Cardiovascular Disease

Povafonidine (PGE-6201204) is a potent α2 adrenoreceptor agonist. Povafonidine can constrict blood vessels and reduce mucosal congestion. Povafonidine can be used for nasal congestion research .
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Referencia número: HY-B0556B
No. CAS: 118201-38-0
Synonyms: Tetryzoline nitrate
Target:  

Adrenergic Receptor

Áreas de investigación:  

Cardiovascular Disease Metabolic Disease

Tetrahydrozoline (Tetryzoline) nitrate , a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline is widely used for the research of nasal congestion and conjunctival congestion .
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Referencia número: HY-B0556AR
No. CAS: 522-48-5
Synonyms: Tetryzoline hydrochloride (Standard)
Tetrahydrozoline (hydrochloride) (Standard) is the analytical standard of Tetrahydrozoline (hydrochloride). This product is intended for research and analytical applications. Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline hydrochloride is widely used for the research of nasal congestion and conjunctival congestion .
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Referencia número: HY-B0556R
No. CAS: 84-22-0
Synonyms: Tetryzoline (Standard)
Áreas de investigación:  

Cardiovascular Disease

Tetrahydrozoline (Standard) is the analytical standard of Tetrahydrozoline. This product is intended for research and analytical applications. Tetrahydrozoline (Tetryzoline), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline is widely used for the research of nasal congestion and conjunctival congestion .
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Referencia número: HY-158194
No. CAS: 928115-79-1
Target:  

Adrenergic Receptor

Áreas de investigación:  

Cancer

α2C adrenoceptor agonist 1 (Compound A) is an orally active, highly selective, and non-central nervous system penetrating agonist for the α2C-adrenoceptor, with EC50 and Ki values of 108 nM and 12 nM, respectively. α2C adrenoceptor agonist 1 can be used in the study of nasal congestion .
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Referencia número: HY-B1317A
No. CAS: 63-56-9
Synonyms: Neohetramine hydrochloride
Target:  

Histamine Receptor

Áreas de investigación:  

Inflammation/Immunology

Thonzylamine hydrochloride is an orally active H1 histamine receptor antagonist with good antihistaminic and antianaphylactic properties. Thonzylamine hydrochloride can be used for the research of hypersensitivity diseases, nasal congestion, allergic conjunctivitis and other allergic diseases .
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Referencia número: HY-B1317R
No. CAS: 91-85-0
Synonyms: Neohetramine (Standard)
Áreas de investigación:  

Inflammation/Immunology

Thonzylamine (Standard) is the analytical standard of Thonzylamine. This product is intended for research and analytical applications. Thonzylamine is an orally active H1 histamine receptor antagonist, exhibits good antihistaminic and antianaphylactic properties. Thonzylamine can be used for the research of hypersensitivity diseases, nasal congestion, allergic conjunctivitis and other allergic diseases .
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Referencia número: HY-109034
No. CAS: 1202265-63-1
Synonyms: AK-272 free base; SCO-272 free base
Áreas de investigación:  

Cardiovascular Disease

Imarikiren (AK-272 free base) is an orally active, selective Renin inhibitor with an IC50 value of 2.1 nM against h-Renin. Imarikiren blocks the conversion of Angiotensinogen to Angiotensin I and reduces mean arterial pressure by inhibiting Angiotensin II that binds to AT1. Imarikiren alleviates myocardial hypertrophy and pulmonary congestion, exerting cardioprotective effects. Imarikiren can be used in research related to hypertension and heart failure .
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Referencia número: HY-182296
No. CAS: 224585-45-9
Target:  

Histamine Receptor

Áreas de investigación:  

Inflammation/Immunology

SCH 79687 is an orally active histamine H3 receptor antagonist, with a Ki of 1.9 nM in rats and 13 nM in guinea pigs. SCH 79687 acts as a competitive antagonist against (R)-α-methylhistamine. SCH 79687 attenuates the inhibitory effect of (R)-α-methylhistamine-induced sympathetic hypertensive responses in guinea pigs. When used in combination with H1 antagonists, SCH 79687 inhibits Compound 48/80 (HY-115768)-induced nasal congestion in cats. SCH 79687 can be used for the research of allergic rhinitis .
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