17 Results for "

congestion

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "congestion" in MCE Product Catalog:

Cat. No.: HY-P990774
CAS No.: 2768386-15-6
Synonyms: ASP-7266; TRAB-1; UPB-101

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Verekitug (ASP-7266; TRAB-1; UPB-101) is a human monoclonal antibody targeting the thymic stromal lymphopoietin receptor (TSLPR), with a mean half-life of approximately 20 days. At doses of Verekitug ≥100 mg, complete and sustained TSLPR-specific occupancy is achieved, and the antibody does not bind to IL-7Rα. By inhibiting TSLP-driven inflammatory responses, Verekitug blocks TSLP-induced cell proliferation and TARC expression, while reducing fractional exhaled NO levels, blood eosinophil counts, and levels of IL-5 and IgE. Verekitug significantly improves scores for nasal polyps, nasal congestion and olfactory dysfunction, with favorable safety and good tolerability; potential adverse reactions include headache, upper respiratory tract infection, sinusitis and nasopharyngitis. Verekitug is used in relevant studies on asthma, chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease .
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Cat. No.: HY-B0556A
CAS No.: 522-48-5
Synonyms: Tetryzoline hydrochloride
Target:  

Adrenergic Receptor

Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline hydrochloride is widely used for the research of nasal congestion and conjunctival congestion .
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Cat. No.: HY-101063
CAS No.: 142457-00-9
Purity:  99.64%
Target:  

Histamine Receptor

Research Areas:  

Inflammation/Immunology

Amthamine is a histamine receptor (H1R-H4R) agonist. Amthamine can produce liver congestion and necrosis of liver cells. Amthamine can be used to study the induction effect of H1R-H4 agonist on hepatotoxicity .
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Cat. No.: HY-B1317
CAS No.: 91-85-0
Synonyms: Neohetramine
Target:  

Histamine Receptor

Research Areas:  

Inflammation/Immunology

Thonzylamine is an orally active H1 histamine receptor antagonist with good antihistaminic and antianaphylactic properties. Thonzylamine can be used for the research of hypersensitivity diseases, nasal congestion, allergic conjunctivitis and other allergic diseases .
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Cat. No.: HY-129508
CAS No.: 142437-67-0
Target:  

Histamine Receptor

Research Areas:  

Inflammation/Immunology

Amthamine is a histamine receptor (H1R-H4R) agonist. Amthamine can produce liver congestion and necrosis of liver cells. Amthamine can be used to study the induction effect of H1R-H4 agonist on hepatotoxicity .
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Cat. No.: HY-B0556
CAS No.: 84-22-0
Synonyms: Tetryzoline
Target:  

Adrenergic Receptor

Research Areas:  

Cardiovascular Disease

Tetrahydrozoline (Tetryzoline), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline is widely used for the research of nasal congestion and conjunctival congestion .
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Cat. No.: HY-B0556AS
CAS No.: 1246814-66-3
Synonyms: Tetryzoline-d4 hydrochloride
Tetrahydrozoline-d4 (hydrochloride) is the deuterium labeled Tetrahydrozoline hydrochloride. Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline hydrochloride is widely used for the research of nasal congestion and conjunctival congestion .
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Cat. No.: HY-109034A
CAS No.: 1202269-24-6
Synonyms: AK-272; SCO-272
Research Areas:  

Cardiovascular Disease

Imarikiren hydrochloride (AK-272) is an orally active, selective Renin inhibitor with an IC50 value of 2.1 nM against h-Renin. Imarikiren hydrochloride blocks the conversion of Angiotensinogen to Angiotensin I and reduces mean arterial pressure by inhibiting Angiotensin II that binds to AT1. Imarikiren hydrochloride alleviates myocardial hypertrophy and pulmonary congestion, exerting cardioprotective effects. Imarikiren hydrochloride can be used in research related to hypertension and heart failure .
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Cat. No.: HY-147299
CAS No.: 177843-85-5
Synonyms: PGE-6201204
Target:  

Adrenergic Receptor

Research Areas:  

Cardiovascular Disease

Povafonidine (PGE-6201204) is a potent α2 adrenoreceptor agonist. Povafonidine can constrict blood vessels and reduce mucosal congestion. Povafonidine can be used for nasal congestion research .
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Cat. No.: HY-B0556B
CAS No.: 118201-38-0
Synonyms: Tetryzoline nitrate
Tetrahydrozoline (Tetryzoline) nitrate , a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline is widely used for the research of nasal congestion and conjunctival congestion .
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Cat. No.: HY-B0556AR
CAS No.: 522-48-5
Synonyms: Tetryzoline hydrochloride (Standard)
Tetrahydrozoline (hydrochloride) (Standard) is the analytical standard of Tetrahydrozoline (hydrochloride). This product is intended for research and analytical applications. Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline hydrochloride is widely used for the research of nasal congestion and conjunctival congestion .
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Cat. No.: HY-B0556R
CAS No.: 84-22-0
Synonyms: Tetryzoline (Standard)
Tetrahydrozoline (Standard) is the analytical standard of Tetrahydrozoline. This product is intended for research and analytical applications. Tetrahydrozoline (Tetryzoline), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline is widely used for the research of nasal congestion and conjunctival congestion .
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Cat. No.: HY-158194
CAS No.: 928115-79-1
Target:  

Adrenergic Receptor

Research Areas:  

Cancer

α2C adrenoceptor agonist 1 (Compound A) is an orally active, highly selective, and non-central nervous system penetrating agonist for the α2C-adrenoceptor, with EC50 and Ki values of 108 nM and 12 nM, respectively. α2C adrenoceptor agonist 1 can be used in the study of nasal congestion .
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Cat. No.: HY-B1317A
CAS No.: 63-56-9
Synonyms: Neohetramine hydrochloride
Target:  

Histamine Receptor

Research Areas:  

Inflammation/Immunology

Thonzylamine hydrochloride is an orally active H1 histamine receptor antagonist with good antihistaminic and antianaphylactic properties. Thonzylamine hydrochloride can be used for the research of hypersensitivity diseases, nasal congestion, allergic conjunctivitis and other allergic diseases .
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Cat. No.: HY-B1317R
CAS No.: 91-85-0
Synonyms: Neohetramine (Standard)
Thonzylamine (Standard) is the analytical standard of Thonzylamine. This product is intended for research and analytical applications. Thonzylamine is an orally active H1 histamine receptor antagonist, exhibits good antihistaminic and antianaphylactic properties. Thonzylamine can be used for the research of hypersensitivity diseases, nasal congestion, allergic conjunctivitis and other allergic diseases .
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Cat. No.: HY-109034
CAS No.: 1202265-63-1
Synonyms: AK-272 free base; SCO-272 free base
Research Areas:  

Cardiovascular Disease

Imarikiren (AK-272 free base) is an orally active, selective Renin inhibitor with an IC50 value of 2.1 nM against h-Renin. Imarikiren blocks the conversion of Angiotensinogen to Angiotensin I and reduces mean arterial pressure by inhibiting Angiotensin II that binds to AT1. Imarikiren alleviates myocardial hypertrophy and pulmonary congestion, exerting cardioprotective effects. Imarikiren can be used in research related to hypertension and heart failure .
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Cat. No.: HY-182296
CAS No.: 224585-45-9
Target:  

Histamine Receptor

Research Areas:  

Inflammation/Immunology

SCH 79687 is an orally active histamine H3 receptor antagonist, with a Ki of 1.9 nM in rats and 13 nM in guinea pigs. SCH 79687 acts as a competitive antagonist against (R)-α-methylhistamine. SCH 79687 attenuates the inhibitory effect of (R)-α-methylhistamine-induced sympathetic hypertensive responses in guinea pigs. When used in combination with H1 antagonists, SCH 79687 inhibits Compound 48/80 (HY-115768)-induced nasal congestion in cats. SCH 79687 can be used for the research of allergic rhinitis .
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