91-85-0
91-85-0
Chemical Structure
Thonzylamine
Synonym(s): Neohetramine
- CAS. Nr.: 91-85-0
- Formula:C16H22N4O
- Molecular Weight:286.37
IUPAC Name: N1-(4-methoxybenzyl)-N2,N2-dimethyl-N1-(pyrimidin-2-yl)ethane-1,2-diamine
InChIKey: GULNIHOSWFYMRN-UHFFFAOYSA-N
SMILES: CN(C)CCN(CC1=CC=C(OC)C=C1)C2=NC=CC=N2
Biological Activity: Thonzylamine is an orally active H1 histamine receptor antagonist with good antihistaminic and antianaphylactic properties. Thonzylamine can be used for the research of hypersensitivity diseases, nasal congestion, allergic conjunctivitis and other allergic diseases[1][2].
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Thonzylamine | 98.05% | Thonzylamine is an orally active H1 histamine receptor antagonist with good antihistaminic and antianaphylactic properties. Thonzylamine can be used for the research of hypersensitivity diseases, nasal congestion, allergic conjunctivitis and other allergic diseases. | ||||||||||||||||||||
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Thonzylamine (Standard) | ≥98% | Thonzylamine (Standard) is the analytical standard of Thonzylamine. This product is intended for research and analytical applications. Thonzylamine is an orally active H1 histamine receptor antagonist, exhibits good antihistaminic and antianaphylactic properties. Thonzylamine can be used for the research of hypersensitivity diseases, nasal congestion, allergic conjunctivitis and other allergic diseases. | ||||||||||||||||||||
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References
- [1]. Zhou S, et, al. Design, synthesis and biological activity of a novel ethylenediamine derivatives as H 1 receptor antagonists. Bioorg Med Chem. 2019 Dec 15; 27(24): 115127. [Content Brief]
- [2]. AARON TH, et, al. Neohetramine and thephorin; two new antihistaminic drugs. Can Med Assoc J. 1948 Nov; 59(5): 438-41. [Content Brief]
Keywords
