63-56-9
Chemical Structure
Thonzylamine hydrochloride
Synonym(s): Neohetramine hydrochloride
- CAS No.: 63-56-9
- Formula:C16H23ClN4O
- Molecular Weight:322.83
IUPAC Name: N1-(4-methoxybenzyl)-N2,N2-dimethyl-N1-(pyrimidin-2-yl)ethane-1,2-diamine hydrochloride
InChIKey: HRYJPHOTGFERGT-UHFFFAOYSA-N
SMILES: COC(C=C1)=CC=C1CN(CCN(C)C)C2=NC=CC=N2.Cl
Biological Activity: Thonzylamine hydrochloride is an orally active H1 histamine receptor antagonist with good antihistaminic and antianaphylactic properties. Thonzylamine hydrochloride can be used for the research of hypersensitivity diseases, nasal congestion, allergic conjunctivitis and other allergic diseases[1][2].
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Thonzylamine hydrochloride | Thonzylamine hydrochloride is an orally active H1 histamine receptor antagonist with good antihistaminic and antianaphylactic properties. Thonzylamine hydrochloride can be used for the research of hypersensitivity diseases, nasal congestion, allergic conjunctivitis and other allergic diseases. | |||||||||||||||||||||
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- [1]. Zhou S, et, al. Design, synthesis and biological activity of a novel ethylenediamine derivatives as H 1 receptor antagonists. Bioorg Med Chem. 2019 Dec 15; 27(24): 115127. [Content Brief]
- [2]. AARON TH, et, al. Neohetramine and thephorin; two new antihistaminic drugs. Can Med Assoc J. 1948 Nov; 59(5): 438-41. [Content Brief]
Keywords
