12 Results for "

cyclin A2

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "cyclin A2" in MCE Product Catalog:

Cat. No.: HY-101257A
CAS No.: 1957203-02-9
Target:  

CDK

Research Areas:  

Cancer

CDK7-IN-1, an analog of YKL-5-124, is a cyclin-dependent kinase 7 (cdk7) inhibitor, with an IC50 of less than 100 nM, extracted from patent WO 2016105528 A2, Compound 215 .
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Cat. No.: HY-170507
CAS No.: 3103862-82-1
Target:  

CDK

Research Areas:  

Cancer

CDK-IN-16 (Compound 5g) is a CDK2/cyclin A2 inhibitor with an IC50 of 1.67 μM. CDK-IN-16 exhibits anticancer activity. The IC50 of CDK-IN-16 against the AGS cell line is 3.5 μM .
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Cat. No.: HY-161826
Target:  

Wnt β-catenin HSP CDK c-Myc

Research Areas:  

Cancer

Antitumor agent-174 (Compound 10) directly engages the N-terminal site of Hsp90 and promotes the degradation of β-catenin, thereby suppressing the Wnt/β-catenin signaling. Antitumor agent-174 effectively inhibits proliferation, induce S and G2/M phases arrest and block the clonogenic ability in CRC cells. Antitumor agent-174 down-regulates CDK1, Cyclin D1, c-Myc, Cyclin B1, and Cyclin A2, and upregulaties P21 proteins. Antitumor agent-174 has significant anti-tumor efficacy against colorectal cancer (CRC) with excellent pharmacokinetics and low toxicity .
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Cat. No.: HY-P83591
Synonyms: CCN1; CCNA; CCNA1; CCNA2; CT146; cyclin-A; cyclin-A1; cyclin-A2

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human

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Cat. No.: HY-P83591A
Synonyms: CCN1; CCNA; CCNA1; CCNA2; CT146; cyclin-A; cyclin-A1; cyclin-A2

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human

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Cat. No.: HY-P86489

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P84166
Synonyms: CCN1; CCNA

Host:  

Mouse

Application:  

WB, IHC-P, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P80096
Synonyms: CCN1, CCNA, CCNA2, cyclin-A2, cyclin-A, cyclin A

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P703551
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCNA2; cyclin-A2; Prev. CCN1; cyclin A; Prev. CCNA; cyclin A2; cyclin-A
Species:  
Source:  
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Cat. No.: HY-P84166A
Synonyms: CCN1; CCNA

Host:  

Mouse

Application:  

WB, IHC-P, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-180222
Target:  

CDK

Research Areas:  

Cancer

KGA-4066 is a novel non-ATP-competitive CDK2 inhibitor. KGA-4066 inhibits CDK2/Cyclin A2 with an IC50 value of 236.7 nM, disrupts their interaction, promots CDK2 degradation via the lysosomal pathway. KGA-4066 has anticancer activity against hepatocellular carcinoma .
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Cat. No.: HY-P702675
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CDK2; CDKN2; cyclin Dependent Kinase 2; Cdc2-Related Protein Kinase; Cell Division Protein Kinase 2; cyclin-Dependent Kinase; cyclin-Dependent Kinase 2; P33(CDK2); P33 Protein Kinase; CCNA2; cyclin-A2; Prev. CCN1; cyclin A; Prev. CCNA; cyclin A2; cyclin-A
Species:  
Source:  
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