1. Cell Cycle/DNA Damage
  2. CDK
  3. CDK7-IN-1

CDK7-IN-1 

Cat. No.: HY-101257A Purity: 99.82%
Handling Instructions

CDK7-IN-1, an analog of YKL-5-124, is a cyclin-dependent kinase 7 (cdk7) inhibitor, with an IC50 of less than 100 nM, extracted from patent WO 2016105528 A2, Compound 215.

For research use only. We do not sell to patients.

CDK7-IN-1 Chemical Structure

CDK7-IN-1 Chemical Structure

CAS No. : 1957203-02-9

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1 mg USD 190 In-stock
Estimated Time of Arrival: December 31
5 mg USD 590 In-stock
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25 mg USD 1990 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

CDK7-IN-1, an analog of YKL-5-124, is a cyclin-dependent kinase 7 (cdk7) inhibitor, with an IC50 of less than 100 nM, extracted from patent WO 2016105528 A2, Compound 215[1].

IC50 & Target[1]

CDK7

100 nM (IC50)

Molecular Weight

517.62

Formula

C₂₈H₃₅N₇O₃

CAS No.

1957203-02-9

SMILES

CC1(C)N(C(N[[email protected]@H](C2=CC=CC=C2)CN(C)C)=O)CC3=C1NN=C3NC(C4=CC=C(NC(CC)=O)C=C4)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
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Keywords:

CDK7-IN-1CDKCyclin dependent kinaseCDK7CDK7/Mat1/CycHtranscriptioncovalentcell-cyclearrestPol-IIphosphorylationT-loopirreversibleInhibitorinhibitorinhibit

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CDK7-IN-1
Cat. No.:
HY-101257A
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