8 Results for "

desfluoro

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "desfluoro" in MCE Product Catalog:

Cat. No.: HY-136059
CAS No.: 302781-98-2
Target:  

Keap1-Nrf2 Autophagy

Research Areas:  

Cardiovascular Disease Cancer

Desfluoro-ezetimibe is a desfluoro impurity of Ezetimibe. Ezetimibe is a potent, metabolically stable cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator .
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Cat. No.: HY-P5372A
Research Areas:  

Cancer

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type' .
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Cat. No.: HY-Z7155
CAS No.: 81886-51-3
Target:  

Fungal

Research Areas:  

Infection

2-Desfluoro fluconazole is an azole antifungal agent .
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Cat. No.: HY-135373
CAS No.: 433289-84-0
Desfluoro-atorvastatin is an impurity of Atorvastatin . Atorvastatin is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, has the ability to effectively decrease blood lipids .
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Cat. No.: HY-167631
CAS No.: 99200-13-2
Target:  

Drug Derivative

Research Areas:  

Others

Desfluoro nebivolol is a desfluorinated Nebivolol (HY-B0203) isomer. Desfluoro nebivolol is a side product of the potent antihypertensive β-blocker Nebivolol .
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Cat. No.: HY-P5373
CAS No.: 237409-87-9
Target:  

Peptides

Research Areas:  

Others

Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2 is a biological active peptide. (Structure-activity studies of thrombin receptor-tethered ligand SFLLRNP have revealed the importance of the Phe-2-phenyl group in receptor recognition and the replacement of the Phe-2 by para-fluorophenylalanine [(p-F)Phe] was found to enhance its activity)
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Cat. No.: HY-P5372
CAS No.: 211190-38-4
Research Areas:  

Cancer

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type' .
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Cat. No.: HY-180955
CAS No.: 773886-89-8
Research Areas:  

Neurological Disease

Desfluoro-BMS-694153 (Compound 3) is a calcitonin gene-related peptide receptor (CGRP receptor) antagonist, with a Ki value of 0.01 nM. Desfluoro-BMS-694153 has a significantly reduced risk of CYP3A4 inhibition, and its IC50 values for CYP3A4-BFC and CYP3A4-BZR are 36 and 6 μM respectively. Desfluoro-BMS-694153 can be used for research on migraines .
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