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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
human LIMK1
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "human LIMK1" in MCE Product Catalog:
Research Areas:
R-10015, a broad-spectrum antiviral compound for HIV infection, acts as a potent and selective inhibitor of LIM domain kinase (LIMK) and binds to the ATP-binding pocket, with an IC50 of 38 nM for human LIMK1 .
Cat. No.: HY-RS07662
Research Areas:
LIMK1 Human Pre-designed siRNA Set A contains three designed siRNAs for LIMK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P705847
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LIMK1; LIMK-1; LIM Domain Kinase 1; LIM Motif-Containing Protein Kinase; LIMK; Uncharacterized Protein LIMK1
Species:
Source:
Cat. No.: HY-P701792
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LIMK1; LIMK-1; LIM Domain Kinase 1; LIM Motif-Containing Protein Kinase; LIMK; Uncharacterized Protein LIMK1
Species:
Source:
Cat. No.: HY-P701793
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LIMK1; LIMK-1; LIM Domain Kinase 1; LIM Motif-Containing Protein Kinase; LIMK; Uncharacterized Protein LIMK1
Species:
Source:
Cat. No.: HY-125444
CAS No.: 1622059-04-4
Target:
Research Areas:
TH251 is a LIMK1 and LIMK2 inhibitor with IC50s of 52 nM and 47 nM against LIMK1 and LIMK2, respectively. TH251 binds to inactive αC-out and DFG-out LIMK1 conformations, inhibits unphosphorylated LIMK1 and LIMK2 enzymatic activity, and exhibits unchanged potency despite PAK-mediated phosphorylation of either kinase. TH251 can be used for the research of cancers, glaucoma, and CNS diseases .
Cat. No.: HY-111103
CAS No.: 2196199-00-3
Target:
Research Areas:
CZh226 is a selective PAK4 inhibitor with an IC50 of 0.0111 μM and a Ki of 0.009 μM. CZh226 functionally inhibits PAK4 activity and reduces the phosphorylation level of downstream signaling molecules. CZh226 inhibits the migration and invasion of tumor cells. CZh226 is applicable to lung cancer-related research .
Cat. No.: HY-P12114
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
