4 Results for "

hydroxycitric acid

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "hydroxycitric acid" in MCE Product Catalog:

1
Hydroxycitric acid
Hydroxycitric acid
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1 Cited Publications
Cat. No.: HY-N1437
CAS No.: 6205-14-7
Category:  

Ketones, Aldehydes, Acids Guttiferae Plants Garcinia gummi-gutta (L.) Roxb.

Target:  

Apoptosis Ferroptosis mTOR DNA/RNA Synthesis Keap1-Nrf2 Ribosomal S6 Kinase (RSK) NF-κB ATP Citrate Lyase AMPK

Hydroxycitric acid is an orally active, multi-target, multi-bioactive organic acid. activates Nrf2 and its downstream molecule GPX4, increases glutathione levels, and thereby inhibits ferroptosis. Hydroxycitric acid activates the Nrf2/Keap1 and ACLY/NF-κB signaling pathways, upregulates the activities of antioxidant enzymes such as superoxide dismutase, reduces MDA content, thereby alleviating oxidative stress and renal tubular epithelial cell apoptosis, and improves pulmonary vascular and right ventricular remodeling. Hydroxycitric acid activates both the AMPK and mTORC1/S6K pathways, triggers the unfolded protein response, arrests the cancer cell cycle, and induces DNA fragmentation .
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1
Hydroxycitric acid tripotassium
Hydroxycitric acid tripotassium
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1 Cited Publications
Cat. No.: HY-W338584
CAS No.: 232281-44-6
Tripotassium hydroxycitrate is an orally active, multi-target, multi-bioactive organic acid. Tripotassium hydroxycitrate activates Nrf2 and its downstream molecule GPX4, increases glutathione levels, and thereby inhibits ferroptosis. Tripotassium hydroxycitrate activates the Nrf2/Keap1 and ACLY/NF-κB signaling pathways, upregulates the activities of antioxidant enzymes such as superoxide dismutase, reduces MDA content, thereby alleviating oxidative stress and renal tubular epithelial cell apoptosis, and improves pulmonary vascular and right ventricular remodeling. Tripotassium hydroxycitrate activates both the AMPK and mTORC1/S6K pathways, triggers the unfolded protein response, arrests the cancer cell cycle, and induces DNA fragmentation .
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(-)-Hydroxycitric acid lactone
(-)-Hydroxycitric acid lactone
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Cat. No.: HY-N7347
CAS No.: 27750-13-6
Synonyms: Garcinia lactone
Category:  

other families Ketones, Aldehydes, Acids Metabolic Disease Plants Disease Research Fields

Target:  

ATP Citrate Lyase

(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent and a popular weight loss food supplement. (-)-Hydroxycitric acid lactone is a potent inhibitor of ATP-citrate lyase. (-)-Hydroxycitric acid lactone catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA, limits the availability of acetyl-CoA units required for fatty acid synthesis .
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(-)-Hydroxycitric acid lactone (Standard)
(-)-Hydroxycitric acid lactone (Standard)
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Cat. No.: HY-N7347R
CAS No.: 27750-13-6
Synonyms: Garcinia lactone (Standard)
Category:  

other families Ketones, Aldehydes, Acids Plants

Target:  

Reference Standards ATP Citrate Lyase

(-)-Hydroxycitric acid lactone (Standard) is the analytical standard of (-)-Hydroxycitric acid lactone. This product is intended for research and analytical applications. (-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent and a popular weight loss food supplement. (-)-Hydroxycitric acid lactone is a potent inhibitor of ATP-citrate lyase. (-)-Hydroxycitric acid lactone catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA, limits the availability of acetyl-CoA units required for fatty acid synthesis .
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