7 Results for "

immune-suppressive

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "immune-suppressive" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-148088
CAS No.: 3027658-65-4
Purity:  98.04%
Target:  

Adenosine Receptor

Research Areas:  

Cancer

M1069 is a selective and orall active, dual A2A/A2B adenosine receptor antagonist with a selectivity of >100 fold against the A1 and A3 receptors. M1069 counteracts immune-suppressive mechanisms of adenosine, and exhibits anti-tumor activity .
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1
1 Cited Publications
Cat. No.: HY-148088A
CAS No.: 2459881-03-7
Purity:  98.92%
Target:  

Adenosine Receptor

Research Areas:  

Cancer

M1069 (free base) is a selective and orall active, dual A2A/A2B adenosine receptor antagonist with a selectivity of >100 fold against the A1 and A3 receptors. M1069 (free base) counteracts immune-suppressive mechanisms of adenosine, and exhibits anti-tumor activity .
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Cat. No.: HY-N0476
CAS No.: 84104-71-2
Synonyms: Regelide; Abruslactone A
Wilforlide A is a bioactive triterpene isolated from Tripterygium wilfordii Hook f. Wilforlide A has anti-inflammatory and immune suppressive effects .
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Cat. No.: HY-179228
CAS No.: 1246964-08-8
Target:  

CTLA-4 TGF-beta/Smad

Research Areas:  

Cancer

AN02 is a derivative of Curcumin (HY-N0005). AN02 inhibits the proliferation and clonogenicity, migration and invasion of ovarian cancer cells. AN02 dose-dependently upregulates the expression of APC and mediates the degradation of CTLA-4 through SMAD4. In the small xenograft model, AN02 significantly inhibits tumor growth and reverses the tumor immune-suppressive microenvironment. AN02, when combined with Ipilimumab (HY-P9901), can enhance efficacy and inhibit epithelial-mesenchymal transition. AN02 can be used for the study of ovarian cancer .
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Cat. No.: HY-N15226
CAS No.: 942986-92-7
Butyrolactone Ia is the inhibitor for the NO production with an IC50 of 18 μM. Butyrolactone Ia inhibits LPS (HY-D1056)-induced mRNA expression of iNOS and the inflammatory cytokine IL-1β. Butyrolactone Ia modulates autophagy in HeLa cells, and exhibits immune suppressive activity .
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Cat. No.: HY-B1214S
Synonyms: Prednisolone 21-acetate-d8
Prednisolone acetate-d8 is the deuterium labeled Prednisolone acetate. Prednisolone acetate (Prednisolone 21-acetate) is an adrenal cortico hormones, with anti-inflammatory, anti-allergic and immune suppressive effects.
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Cat. No.: HY-N0476R
CAS No.: 84104-71-2
Synonyms: Regelide (Standard); Abruslactone A (Standard)
Wilforlide A (Standard) is the analytical standard of Wilforlide A. This product is intended for research and analytical applications. Wilforlide A is a bioactive triterpene isolated from Tripterygium wilfordii Hook f. Wilforlide A has anti-inflammatory and immune suppressive effects .
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