942986-92-7
942986-92-7
Chemical Structure
Butyrolactone Ia
- CAS No.: 942986-92-7
- Formula:C23H22O7
- Molecular Weight:410.42
InChIKey: VNNVZMRLAYBBMS-HSZRJFAPSA-N
SMILES: OC([C@]1(C(C2=CC=C(C=C2)O)=C(C(O1)=O)O)CC3=CC(C/C=C(C)\C)=C(C=C3)O)=O
Biological Activity: Butyrolactone Ia is the inhibitor for the NO production with an IC50 of 18 μM. Butyrolactone Ia inhibits LPS (HY-D1056)-induced mRNA expression of iNOS and the inflammatory cytokine IL-1β. Butyrolactone Ia modulates autophagy in HeLa cells, and exhibits immune suppressive activity[1].
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Butyrolactone Ia | Butyrolactone Ia is the inhibitor for the NO production with an IC50 of 18 μM. Butyrolactone Ia inhibits LPS (HY-D1056)-induced mRNA expression of iNOS and the inflammatory cytokine IL-1β. Butyrolactone Ia modulates autophagy in HeLa cells, and exhibits immune suppressive activity. | |||||||||||||||||||||
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References
Keywords
