12 Results for "

leukopenia

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "leukopenia" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-B1184
CAS No.: 50-12-4
Target:  

Cytochrome P450

Research Areas:  

Neurological Disease

Mephenytoin, an anticonvulsant, is the CYP2C19 and CYP2B6 substrate .
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1
1 Cited Publications
Cat. No.: HY-N0620
CAS No.: 102841-43-0
Mulberroside C is one of the main bioactive components in white mulberry (Morus alba L.). Mulberroside C exhibits antiplatelet, antiviral and neutrophil-regulating activities, and binds to EV-A71 VP1 with a Kd value of 1.289 nM. Mulberroside C reduces the phosphorylation level of ERK, promotes the phosphorylation of IP3RI at the Ser 1756 site, and decreases calcium influx and calcium mobilization. Mulberroside C inhibits the expression of P-selectin (P-selectin). Mulberroside C upregulates the cyclic nucleotide signaling pathway in human platelets. Mulberroside C binds to IL-23R, upregulates the expression of G-CSF, GM-CSF and RASGRP1, and activates the RAS/ERK signaling pathway. Mulberroside C promotes neutrophil maturation, accelerates the recovery of leukopenia, and enhances the antibacterial activity of neutrophils. Mulberroside C inhibits the replication of hepatitis C virus in replicon cells. Mulberroside C prevents the uncoating and genome release of EV-A71, and inhibits the synthesis of viral proteins and RNA. Mulberroside C can be used in studies related to thrombosis-mediated cardiovascular diseases, chemotherapy- and radiotherapy-induced leukopenia, hepatitis C virus infection, and hand, foot and mouth disease .
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Cat. No.: HY-15491
CAS No.: 837364-57-5
Purity:  98.53%
Target:  

COX Apoptosis

Research Areas:  

Cancer

AG-024322 is a potent ATP-competitive pan-CDK inhibitor against cell cycle kinases CDK1, CDK2, and CDK4 with Ki values in the 1-3 nM range . AG-024322 displays broad-spectrum anti-tumor activity and clear target modulation in vivo. AG-024322 induces cell apoptosis .
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Cat. No.: HY-134181A
CAS No.: 9075-53-0
Tremella polysaccharide, MW<1000000, cosmetic grade, one of the fungus polysaccharides, possesses immunity enhancing capabilities. Polysaccharidase has the potential for leukopenia induced by chemotherapy and radiotherapy research .
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Cat. No.: HY-118028
CAS No.: 1950-36-3
Purity:  99.99%
Leyk is an orally active Cysteine derivative. Leyk stimulates bone marrow hematopoiesis. Leyk exerts a significant protective effect against cyclophosphamide-induced leukopenia. Leyk can be used in studies related to thrombocytopenia and leukopenia .
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Cat. No.: HY-134181
CAS No.: 9075-53-0
Tremella polysaccharide, MW>1000000, cosmetic grade, one of the fungus polysaccharides, possesses immunity enhancing capabilities. Polysaccharidase has the potential for leukopenia induced by chemotherapy and radiotherapy research .
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Cat. No.: HY-106091B
CAS No.: 88303-61-1
Synonyms: CI 941 hydrochloride; DUP 94 hydrochloride
Research Areas:  

Cancer

Losoxantrone hydrochloride (CI 941 hydrochloride) is a DNA-binding agent. Losoxantrone hydrochloride has broad-spectrum antitumour activity. Losoxantrone hydrochloride induces dose-dependent leukopenia .
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Cat. No.: HY-111984A
CAS No.: 7262-00-2
Target:  

Adrenergic Receptor

Research Areas:  

Cardiovascular Disease

Quinazosin dihydrochloride is an antihypertensive α1-adrenergic receptor antagonist whose activity is associated with inhibition of granulopoiesis, resulting in neutropenia and leukopenia. Quinazosin dihydrochloride exhibits dose-related myelosuppression that is correlated with the duration of suppression .
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Cat. No.: HY-B1184R
CAS No.: 50-12-4
Research Areas:  

Neurological Disease

Mephenytoin (Standard) is the analytical standard of Mephenytoin. This product is intended for research and analytical applications. Mephenytoin, an anticonvulsant, is the CYP2C19 and CYP2B6 substrate .
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Cat. No.: HY-117569
CAS No.: 178750-21-5
Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

KF24345 free base is an orally active adenosine uptake inhibitor. KF24345 free base inhibits adenosine uptake by human, mouse, rabbit and hamster erythrocytes with IC50 values of 59.5, 130.1, 104.2 and 30.9 nM, respectively. KF24345 free base has anti-inflammatory activity and can inhibit LPS-induced TNF-α production and leukopenia in mice .
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Cat. No.: HY-106091
CAS No.: 88303-60-0
Synonyms: CI 941; DuP-941; Biantrazole
Research Areas:  

Cancer

Losoxantrone (CI 941) is a DNA-binding agent. Losoxantrone has broad-spectrum antitumour activity. Losoxantrone induces dose-dependent leukopenia .
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Cat. No.: HY-119869
CAS No.: 77658-97-0
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Anaxirone is an anti-tumor agent. The epoxy group in its structure can interfere with the proliferation of tumor cells by alkylating biological macromolecules such as DNA. Anaxirone has dose-limiting toxicity (DLT) and gastrointestinal toxicity. Anaxirone can be used for research on solid tumors such as non-small cell lung cancer (NSCLC) .
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