4 Results for "

liver-derived cells

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "liver-derived cells" in MCE Product Catalog:

Cat. No.: HY-168046
CAS No.: 2542029-03-6
Research Areas:  

Metabolic Disease

ALG-055009 is a selective and orally active Thyroid Hormone Receptor Beta (THR-β) agonist with an EC50 of 0.063 μM. ALG-055009 binds to the T3 hormone pocket of human THR-β, forming polar interactions with protein residues. ALG-055009 can lower total cholesterol levels in rats on a high-fat diet. ALG-055009 exhibits high metabolic stability, good permeability, a long in vivo half-life, and limited drug-drug interaction liability. ALG-055009 can be used in studies related to metabolic dysfunction-associated fatty liver disease .
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Cat. No.: HY-147917
CAS No.: 2891451-33-3
Research Areas:  

Cancer

RNA polymerase II-IN-2 is a RNA polymerase II inhibitor with a Ki value of 74.1 nM. RNA polymerase II-IN-2 inhibits Pol II-mediated transcription and induces cytotoxicity in mammalian cells. RNA polymerase II-IN-2 serves as a payload for antibody-drug conjugates (ADC) and is applicable for cancer research .
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Cat. No.: HY-E72115
Target:  

UGT

Research Areas:  

Others

Human UGT2B17 is a UDP-glucuronosyltransferase. Human UGT2B17 catalyzes the glucuronidation of Testosterone at the 17β-OH position, binds Epitestosteron with comparable affinity, but cannot catalyze its glucuronidation .
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Cat. No.: HY-N17652
CAS No.: 1308347-24-1
13′-Hydroxy-δ-tocopherol is a metabolite of long-chain vitamin E. 13′-Hydroxy-δ-tocopherol can induces cells apoptosis and minor reduction in mitochondrial membrane potential. 13′-Hydroxy-δ-tocopherol can be used for the research of hepatocellular carcinoma .
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