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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
mitoNEET
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "mitoNEET" in MCE Product Catalog:
5
5 Cited Publications
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NL-1 is a mitoNEET inhibitor with antileukemic effect. NL-1 inhibits REH and REH/Ara-C cells growth with IC50s of 47.35 μM and 56.26 μM, respectively. NL-1-mediated death in leukemic cells requires the activation of the autophagic pathway .
1
1 Cited Publications
Cat. No.: HY-P76262
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CISD1; CDGSH Iron-Sulfur Domain-Containing Protein 1; Prev. C10orf70; Chromosome 10 Open Reading Frame 70; Prev. ZCD1; Zinc Finger, CDGSH-Type Domain 1; mitoNEET; Zinc Finger CDGSH-Type Domain 1; MDS029; CDGSH Iron Sulfur Domain 1; Cysteine Transaminase C
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TT01001 is a selective and orally active mitoNEET agonist and a monoamine oxidase B (MAO-B) inhibitor (IC50 = 8.84 μM). TT01001 does not activate PPARγ but interacts with MitoNEET. TT01001 attenuates oxidative stress and neuronal apoptosis by preventing mitoNEET-mediated mitochondrial dysfunction. TT01001 improves type II diabetes and ameliorates mitochondrial function of mice. TT01001 can used for the studies of type II diabetes and neurological disorders .
Cat. No.: HY-RS17379
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Cisd1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cisd1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02723
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CISD1 Human Pre-designed siRNA Set A contains three designed siRNAs for CISD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23833
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Cisd1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cisd1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
