188532-26-5
188532-26-5
Chemical Structure
NL-1
- CAS No.: 188532-26-5
- Formula:C18H25NO3S
- Molecular Weight:335.46
IUPAC Name: 5-(3,5-di-tert-butyl-4-hydroxybenzyl)thiazolidine-2,4-dione
InChIKey: QDYYSPGKYXWGSL-UHFFFAOYSA-N
SMILES: O=C(N1)SC(CC2=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C2)C1=O
Biological Activity: NL-1 is a mitoNEET inhibitor with antileukemic effect. NL-1 inhibits REH and REH/Ara-C cells growth with IC50s of 47.35 μM and 56.26 μM, respectively. NL-1-mediated death in leukemic cells requires the activation of the autophagic pathway[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NL-1 | 99.45% | NL-1 is a mitoNEET inhibitor with antileukemic effect. NL-1 inhibits REH and REH/Ara-C cells growth with IC50s of 47.35 μM and 56.26 μM, respectively. NL-1-mediated death in leukemic cells requires the activation of the autophagic pathway. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.84
HY-137789Tazofelone -
Similarity Score 0.67
HY-W009347COX-1-IN-3 -
Similarity Score 0.66
HY-103503CGP13501 -
Similarity Score 0.66
HY-101579LY 178002 -
Similarity Score 0.65
HY-103253LY231617 -
Similarity Score 0.65
HY-111060LY231617 free base -
Similarity Score 0.64
HY-103502CGP7930 -
Similarity Score 0.64
HY-W0121873,5-Di-tert-butyl-4-hydroxybenzaldehyde -
Similarity Score 0.64
HY-114873LY256548 -
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