11 Results for "

mouse CD1d

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "mouse CD1d" in MCE Product Catalog:

Cat. No.: HY-P990273

Target:  

CD38 ERK CD1 Apoptosis

Research Areas:  

Cancer

Anti-Mouse CD38 Antibody (NIMR5) is an anti-mouse CD38 IgG2a monoclonal antibody. Anti-Mouse CD38 Antibody (NIMR5) can activate the ERK signaling pathway and promote cell apoptosis. Anti-Mouse CD38 Antibody (NIMR5) can restore T cell function. Anti-Mouse CD38 Antibody (NIMR5) upregulates the expression of CD1d protein and enhances spleen cell proliferation, dendritic cell (DC) and natural killer T cell (NKT) expansion. Anti-Mouse CD38 Antibody (NIMR5) can be used for researches on cancer and immunology such as melanoma and colon cancer .
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Cat. No.: HY-P990287

Target:  

CD1

Research Areas:  

Inflammation/Immunology

Anti-Mouse CD1d Antibody (19G11) is a rat-derived IgG1 type antibody inhibitor, targeting to mouse CD1d. Anti-Mouse CD1d Antibody (19G11) can neutralize CD1d and inhibit the activation of invariant natural killer T (iNKT) cells. Anti-Mouse CD1d Antibody (19G11) can be used for the researches of inflammation and immunology, such as colitis .
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Cat. No.: HY-P990807

Target:  

CD1

Anti-Mouse CD1d Antibody (20H2 (HB323)) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse CD1d. Anti-Mouse CD1d Antibody (20H2 (HB323)) can block CD1d and neutralize invariant natural killer T (iNKT) cells. Anti-Mouse CD1d Antibody (20H2 (HB323)) can be used for the researches of cancer, infection, inflammation and immunology, such as melanoma, L. monocytogenes infection and arthritis .
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Cat. No.: HY-P992059

Target:  

CD1

Research Areas:  

Cancer

Anti-Mouse CD1d Antibody (1B1) is an antibody targeting mouse CD1d (Kd=12.5 nM). By inserting into the lipid-binding groove of CD1d, Anti-Mouse CD1d Antibody (1B1) overlaps with the binding sites of type I and type II NKT cell receptors (TCR), thereby effectively blocking TCR-mediated interactions. Anti-Mouse CD1d Antibody (1B1) activates antigen-presenting cells such as dendritic cells and macrophages, induces them to release IL-12p70, and increases the levels of key cytokines including IL-12, IFN-γ and IFN-α in mouse serum. Anti-Mouse CD1d Antibody (1B1) can be used in studies related to renal cancer, breast cancer and colon adenocarcinoma. When combined with anti-DR5 or anti-CD137 antibodies and chemotherapeutic drugs, Anti-Mouse CD1d Antibody (1B1) exhibits significant tumor inhibitory and even eradication effects in mice .
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Cat. No.: HY-P991846

Target:  

CD1

Research Areas:  

Inflammation/Immunology

Anti-CD1d Antibody (D5) reacts with the human CD1d. CD1d belongs to the cluster of differentiation 1 (CD1) family of glycoproteins. Recommend Isotype Controls: Mouse IgG2b kappa, Isotype Control (HY-P99982) .
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Cat. No.: HY-P75437
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD1.1; CD1d1; CD1d.1; Antigen-presenting glycoprotein CD1d1
Species:  
Source:  
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Cat. No.: HY-P75436
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: CD1.1; CD1d1; CD1d.1; Antigen-presenting glycoprotein CD1d1
Species:  
Source:  
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Cat. No.: HY-P76778
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD1.1; CD1d1; CD1d.1; Antigen-presenting glycoprotein CD1d1; B2M; Beta 2-Microglobulin; Beta-2-Microglobulin; Beta-2-Microglobin; Beta Chain Of MHC Class I Molecules; AMYLD6; Beta 2-Microglobulin Protein; MHC1d4; Human Nkt Tcr Alpha Chain; IMD43; Human Nk
Species:  
Source:  
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Cat. No.: HY-P76779
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Antigen-presenting glycoprotein CD1d2; CD1d.2; CD1d2; CD1.2; B2M; Beta 2-Microglobulin; Beta-2-Microglobulin; Beta-2-Microglobin; Beta Chain Of MHC Class I Molecules; AMYLD6; Beta 2-Microglobulin Protein; MHC1d4; Human Nkt Tcr Alpha Chain; IMD43; Human Nk
Species:  
Source:  
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Cat. No.: HY-181739
Target:  

CD1

Research Areas:  

Cancer

GCB-27a is a CD1d-binding immunostimulant and antitumor agent. GCB-27a binds to CD1d to form a stable complex and presents it to NKT cells, enhancing hydrophobic interactions within the A' pocket of CD1d through branched-chain conformation restriction. GCB-27a induces a Th1-biased immune response, drives IFN?γ production and limits IL-4 levels. GCB-27a is applicable to research related to melanoma lung metastasis .
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Cat. No.: HY-181740
Target:  

CD1

Research Areas:  

Cancer

GCB-27b is an immunostimulant that binds to CD1d. GCB-27b forms a stable and long-lasting complex with CD1d, which is presented to the TCR of NKT cells to drive immune responses. GCB-27b induces a Th1-skewed immune response in *Mus musculus*, resulting in high expression of IFN?γ with restricted IL-4 levels. GCB-27b is applicable to research related to lung metastasis of melanoma .
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