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mouse CD1d

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CD1 (7) CD38 (1) Apoptosis (1) ERK (1)
By Research Areas:	Cancer (5) Infection (1) Inflammation/Immunology (4)

7

Inhibitors & Agonists

5

Inhibitory Antibodies

4

Recombinant Proteins

Targets Recommended: CD1 CD38 CD28 CD19 CD20 CD22 Transferrin Receptor CD3 P-selectin CD6 CD2 CD276/B7-H3 CD73 c-Kit LAG-3 L-Selectin CTLA-4 CD47 ALCAM/CD166 Neprilysin E-Selectin Scavenger Receptor Class B type I (SR-BI） FLT3 Tim3 CD44 Anaplastic lymphoma kinase (ALK) CD74 Human leukocyte immunoglobulin (Ig)-like receptors (LILR) P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Anti-Mouse CD38 Antibody (NIMR5)	CD38 ERK CD1 Apoptosis	Inflammation/Immunology Cancer
Anti-Mouse CD38 Antibody (NIMR5) is an anti-mouse CD38 IgG2a monoclonal antibody. Anti-Mouse CD38 Antibody (NIMR5) can activate the ERK signaling pathway and promote cell apoptosis. Anti-Mouse CD38 Antibody (NIMR5) can restore T cell function. Anti-Mouse CD38 Antibody (NIMR5) upregulates the expression of *CD1d* protein and enhances spleen cell proliferation, dendritic cell (DC) and natural killer T cell (NKT) expansion. Anti-Mouse CD38 Antibody (NIMR5) can be used for researches on cancer and immunology such as melanoma and colon cancer .

*Anti-Mouse* CD1d Antibody (19G11)**	CD1	Inflammation/Immunology
Anti-Mouse CD1d Antibody (19G11) is a rat-derived IgG1 type antibody inhibitor, targeting to mouse *CD1d. Anti-Mouse* CD1d Antibody (19G11) can neutralize CD1d and inhibit the activation of invariant natural killer T (iNKT) cells. Anti-Mouse CD1d Antibody (19G11) can be used for the researches of inflammation and immunology, such as colitis .

*Anti-Mouse* CD1d Antibody (20H2 (HB323))**	CD1	Infection Inflammation/Immunology Cancer
Anti-Mouse CD1d Antibody (20H2 (HB323)) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse *CD1d. Anti-Mouse* CD1d Antibody (20H2 (HB323)) can block CD1d and neutralize invariant natural killer T (iNKT) cells. Anti-Mouse CD1d Antibody (20H2 (HB323)) can be used for the researches of cancer, infection, inflammation and immunology, such as melanoma, L. monocytogenes infection and arthritis .

*Anti-Mouse* CD1d Antibody (1B1)**	CD1	Cancer
Anti-Mouse CD1d Antibody (1B1) is an antibody targeting mouse *CD1d* (K_d=12.5 nM). By inserting into the lipid-binding groove of *CD1d, Anti-Mouse* CD1d Antibody (1B1) overlaps with the binding sites of type I and type II NKT cell receptors (TCR), thereby effectively blocking TCR-mediated interactions. Anti-Mouse CD1d Antibody (1B1) activates antigen-presenting cells such as dendritic cells and macrophages, induces them to release IL-12p70, and increases the levels of key cytokines including IL-12, IFN-γ and IFN-α in mouse serum. Anti-Mouse CD1d Antibody (1B1) can be used in studies related to renal cancer, breast cancer and colon adenocarcinoma. When combined with anti-DR5 or anti-CD137 antibodies and chemotherapeutic drugs, Anti-Mouse CD1d Antibody (1B1) exhibits significant tumor inhibitory and even eradication effects in mice .

Anti-CD1d Antibody (D5)	CD1	Inflammation/Immunology
Anti-CD1d Antibody (D5) reacts with the human CD1d. CD1d belongs to the cluster of differentiation 1 (CD1) family of glycoproteins. Recommend Isotype Controls: Mouse IgG2b kappa, Isotype Control (HY-P99982) .

GCB-27a	CD1	Cancer
GCB-27a is a CD1d-binding immunostimulant and antitumor agent. GCB-27a binds to CD1d to form a stable complex and presents it to NKT cells, enhancing hydrophobic interactions within the A' pocket of CD1d through branched-chain conformation restriction. GCB-27a induces a Th1-biased immune response, drives IFN−γ production and limits IL-4 levels. GCB-27a is applicable to research related to melanoma lung metastasis .

GCB-27b	CD1	Cancer
GCB-27b is an immunostimulant that binds to CD1d. GCB-27b forms a stable and long-lasting complex with CD1d, which is presented to the TCR of NKT cells to drive immune responses. GCB-27b induces a Th1-skewed immune response in Mus musculus, resulting in high expression of IFN−γ with restricted IL-4 levels. GCB-27b is applicable to research related to lung metastasis of melanoma .

Cat. No.	Product Name	Target	Research Area	Image

Anti-Mouse CD38 Antibody (NIMR5)	CD38 ERK CD1 Apoptosis	Inflammation/Immunology Cancer
Anti-Mouse CD38 Antibody (NIMR5) is an anti-mouse CD38 IgG2a monoclonal antibody. Anti-Mouse CD38 Antibody (NIMR5) can activate the ERK signaling pathway and promote cell apoptosis. Anti-Mouse CD38 Antibody (NIMR5) can restore T cell function. Anti-Mouse CD38 Antibody (NIMR5) upregulates the expression of *CD1d* protein and enhances spleen cell proliferation, dendritic cell (DC) and natural killer T cell (NKT) expansion. Anti-Mouse CD38 Antibody (NIMR5) can be used for researches on cancer and immunology such as melanoma and colon cancer .

*Anti-Mouse* CD1d Antibody (19G11)**	CD1	Inflammation/Immunology
Anti-Mouse CD1d Antibody (19G11) is a rat-derived IgG1 type antibody inhibitor, targeting to mouse *CD1d. Anti-Mouse* CD1d Antibody (19G11) can neutralize CD1d and inhibit the activation of invariant natural killer T (iNKT) cells. Anti-Mouse CD1d Antibody (19G11) can be used for the researches of inflammation and immunology, such as colitis .

*Anti-Mouse* CD1d Antibody (20H2 (HB323))**	CD1	Infection Inflammation/Immunology Cancer
Anti-Mouse CD1d Antibody (20H2 (HB323)) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse *CD1d. Anti-Mouse* CD1d Antibody (20H2 (HB323)) can block CD1d and neutralize invariant natural killer T (iNKT) cells. Anti-Mouse CD1d Antibody (20H2 (HB323)) can be used for the researches of cancer, infection, inflammation and immunology, such as melanoma, L. monocytogenes infection and arthritis .

*Anti-Mouse* CD1d Antibody (1B1)**	CD1	Cancer
Anti-Mouse CD1d Antibody (1B1) is an antibody targeting mouse *CD1d* (K_d=12.5 nM). By inserting into the lipid-binding groove of *CD1d, Anti-Mouse* CD1d Antibody (1B1) overlaps with the binding sites of type I and type II NKT cell receptors (TCR), thereby effectively blocking TCR-mediated interactions. Anti-Mouse CD1d Antibody (1B1) activates antigen-presenting cells such as dendritic cells and macrophages, induces them to release IL-12p70, and increases the levels of key cytokines including IL-12, IFN-γ and IFN-α in mouse serum. Anti-Mouse CD1d Antibody (1B1) can be used in studies related to renal cancer, breast cancer and colon adenocarcinoma. When combined with anti-DR5 or anti-CD137 antibodies and chemotherapeutic drugs, Anti-Mouse CD1d Antibody (1B1) exhibits significant tumor inhibitory and even eradication effects in mice .

Anti-CD1d Antibody (D5)	CD1	Inflammation/Immunology
Anti-CD1d Antibody (D5) reacts with the human CD1d. CD1d belongs to the cluster of differentiation 1 (CD1) family of glycoproteins. Recommend Isotype Controls: Mouse IgG2b kappa, Isotype Control (HY-P99982) .

Species:	Mouse (4)
Tag:	His (4) Fc (1)
Source:	HEK293 (4)

Cat. No.	Compare	Product Name	Species	Source	Image

	CD1D Protein, Mouse (HEK293, His) Antigen-presenting glycoprotein CD1d; CD1d; R3G1	Mouse	HEK293
	CD1D protein, in partnership with B2M, functions as an antigen-presenting protein, binding self and non-self glycolipids. It presents these molecules to T-cell receptors on natural killer T-cells, playing a pivotal role in immune responses. CD1D also interacts with MHC II and CD74, contributing to the coordination of the adaptive immune system. CD1D Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD1D protein, expressed by HEK293 , with C-His labeled tag.

	CD1D Protein, Mouse (HEK293, His-Fc) Antigen-presenting glycoprotein CD1d; CD1d; R3G1	Mouse	HEK293
	CD1D protein, in partnership with B2M, functions as an antigen-presenting protein, binding self and non-self glycolipids. It presents these molecules to T-cell receptors on natural killer T-cells, playing a pivotal role in immune responses. CD1D also interacts with MHC II and CD74, contributing to the coordination of the adaptive immune system. CD1D Protein, Mouse (HEK293, His-Fc) is the recombinant mouse-derived CD1D protein, expressed by HEK293 , with C-hFc, C-His labeled tag.

	CD1D1-B2M Heterodimer Protein, Mouse (HEK293, His) Antigen-presenting glycoprotein CD1d1; CD1d1; Beta-2-microglobulin	Mouse	HEK293
	CD1D protein, in partnership with B2M, functions as an antigen-presenting protein, binding self and non-self glycolipids. It presents these molecules to T-cell receptors on natural killer T-cells, playing a pivotal role in immune responses. CD1D also interacts with MHC II and CD74, contributing to the coordination of the adaptive immune system. CD1D1-B2M Heterodimer Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived CD1D1-B2M Heterodimer protein, expressed by HEK293 , with C-His labeled tag. CD1D1-B2M Heterodimer Protein, Mouse (HEK293, His), has molecular weight of ~40-50 & 12 KDa, respectively.

	CD1D2-B2M Heterodimer Protein, Mouse (HEK293, His) Antigen-presenting glycoprotein CD1d2; CD1d2; Beta-2-microglobulin	Mouse	HEK293
	The CD1D2 protein plays a crucial role as an antigen-presenting molecule, binding self and non-self glycolipids and presenting them to T-cell receptors on natural killer T-cells. In partnership with B2M, it mediates immune responses, and its interactions with MHC II and CD74 highlight its significance in the complex network of immune system regulation. CD1D2-B2M Heterodimer Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived CD1D2-B2M Heterodimer protein, expressed by HEK293 , with C-His labeled tag.

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