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  5. CD1D2-B2M Heterodimer Protein, Mouse (HEK293, His)

CD1D2-B2M Heterodimer Protein, Mouse (HEK293, His)

Cat. No.: HY-P76779
Handling Instructions

The CD1D2 protein plays a crucial role as an antigen-presenting molecule, binding self and non-self glycolipids and presenting them to T-cell receptors on natural killer T-cells. In partnership with B2M, it mediates immune responses, and its interactions with MHC II and CD74 highlight its significance in the complex network of immune system regulation. CD1D2-B2M Heterodimer Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived CD1D2-B2M Heterodimer protein, expressed by HEK293, with C-His labeled tag. CD1D2-B2M Heterodimer Protein, Mouse (HEK293, His), has molecular weight of ~33.7 & 11.7 KDa, respectively.

For research use only. We do not sell to patients.

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Description

The CD1D2 protein plays a crucial role as an antigen-presenting molecule, binding self and non-self glycolipids and presenting them to T-cell receptors on natural killer T-cells. In partnership with B2M, it mediates immune responses, and its interactions with MHC II and CD74 highlight its significance in the complex network of immune system regulation. CD1D2-B2M Heterodimer Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived CD1D2-B2M Heterodimer protein, expressed by HEK293, with C-His labeled tag. CD1D2-B2M Heterodimer Protein, Mouse (HEK293, His), has molecular weight of ~33.7 & 11.7 KDa, respectively.

Background

The CD1D2-B2M heterodimer protein serves as a pivotal antigen-presenting molecule, with the ability to bind both self and non-self glycolipids and subsequently present them to T-cell receptors on natural killer T-cells. In its heterodimeric partnership with B2M (beta-2-microglobulin), CD1D2 plays a crucial role in mediating immune responses. Notably, its interactions with MHC II and CD74 further underscore its significance within the intricate network of immune system regulation.

Species

Mouse

Source

HEK293

Tag

C-His

Accession

P11610 (Q22-G305)&P01887 (I21-M119)

Gene ID

12480  [NCBI]&12010  [NCBI]

Synonyms
Antigen-presenting glycoprotein CD1d2; Cd1d2; Beta-2-microglobulin
Molecular Weight

Approximately 33.7&11.7 kDa.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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CD1D2-B2M Heterodimer Protein, Mouse (HEK293, His)
Cat. No.:
HY-P76779
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