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  5. CD1D1-B2M Heterodimer Protein, Mouse (HEK293, His)

CD1D1-B2M Heterodimer Protein, Mouse (HEK293, His)

Cat. No.: HY-P76778
Handling Instructions

CD1D protein, in partnership with B2M, functions as an antigen-presenting protein, binding self and non-self glycolipids. It presents these molecules to T-cell receptors on natural killer T-cells, playing a pivotal role in immune responses. CD1D also interacts with MHC II and CD74, contributing to the coordination of the adaptive immune system. CD1D1-B2M Heterodimer Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived CD1D1-B2M Heterodimer protein, expressed by HEK293, with C-His labeled tag. CD1D1-B2M Heterodimer Protein, Mouse (HEK293, His), has molecular weight of ~33.7 & 11.7 KDa, respectively.

For research use only. We do not sell to patients.

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  • Biological Activity

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Description

CD1D protein, in partnership with B2M, functions as an antigen-presenting protein, binding self and non-self glycolipids. It presents these molecules to T-cell receptors on natural killer T-cells, playing a pivotal role in immune responses. CD1D also interacts with MHC II and CD74, contributing to the coordination of the adaptive immune system. CD1D1-B2M Heterodimer Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived CD1D1-B2M Heterodimer protein, expressed by HEK293, with C-His labeled tag. CD1D1-B2M Heterodimer Protein, Mouse (HEK293, His), has molecular weight of ~33.7 & 11.7 KDa, respectively.

Background

The CD1D protein serves as an antigen-presenting protein capable of binding both self and non-self glycolipids, presenting them to T-cell receptors on natural killer T-cells. Forming a heterodimer with B2M (beta-2-microglobulin), CD1D plays a crucial role in immune responses. Additionally, it interacts with MHC II and CD74, contributing to the orchestration of the adaptive immune system.

Species

Mouse

Source

HEK293

Tag

C-His

Accession

P11609 (Q22-S297)&P01887 (I21-M119)

Gene ID

12479  [NCBI]&12010  [NCBI]

Synonyms
Antigen-presenting glycoprotein CD1d1; Cd1d1; Beta-2-microglobulin
Molecular Weight

Approximately 33.7&11.7 kDa.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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CD1D1-B2M Heterodimer Protein, Mouse (HEK293, His)
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HY-P76778
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