Anti-Mouse CD1d Antibody (19G11) 

Anti-Mouse CD1d Antibody (19G11) is a rat-derived IgG1 type antibody inhibitor, targeting to mouse CD1d. Anti-Mouse CD1d Antibody (19G11) can neutralize CD1d and inhibit the activation of invariant natural killer T (iNKT) cells. Anti-Mouse CD1d Antibody (19G11) can be used for the researches of inflammation and immunology, such as colitis^[1][2].

Rat IgG1

Rat IgG1 kappa, Isotype Control

Mouse

CD1d

Anti-Mouse CD1d Antibody (19G11) inhibits the activation of invariant natural killer T (iNKT) cells in dendritic cells^[1].
Anti-Mouse CD1d Antibody (19G11) (10 μg/mL) blocks CD1d in MODE-K cells^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-Mouse CD1d Antibody (19G11) (1 mg, i.p., before skin sensitization and before and 2 days after Oxazolone) reduces the severity of colitis in Oxazolone (HY-126360)-induced colitis mice^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

12479  [NCBI]

P11609

in vivo CD1d neutralization; in vitro CD1d neutralization

Unconjugated

The product can be reconstituted/diluted with sterile PBS or saline.

150 kDa

Liquid

Colorless to light yellow

[Anti-Mouse CD1d Antibody (19G11)]

Please refer to the lot-specific COA for specific buffer information.

Please store the product under the recommended conditions in the Certificate of Analysis.

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• [1]. Melum E, et al. Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin. Nat Immunol. 2019 Dec;20(12):1644-1655.  [Content Brief]

  [2]. Olszak T, et al. Protective mucosal immunity mediated by epithelial CD1d and IL-10. Nature. 2014 May 22;509(7501):497-502.  [Content Brief]