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Cat. No.: HY-P990287

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Anti-Mouse CD1d Antibody (19G11)

Name: Anti-Mouse CD1d Antibody (19G11)
Brand: MedChemExpress
SKU: HY-P990287
Price: 220.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Based on 1 Customer Validation

Anti-Mouse CD1d Antibody (19G11) is a rat-derived IgG1 type antibody inhibitor, targeting to mouse CD1d. Anti-Mouse CD1d Antibody (19G11) can neutralize CD1d and inhibit the activation of invariant natural killer T (iNKT) cells. Anti-Mouse CD1d Antibody (19G11) can be used for the researches of inflammation and immunology, such as colitis.

For research use only. We do not sell to patients.

Purity: 95.00%
Molecular Weight:150 kDa

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Anti-Mouse CD1d Antibody (19G11) Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- IC₅₀ & Target
- In Vitro
- In Vivo
- Gene ID
- Accession
- Conjugated
- Reconsititution
- Format
- Application
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Isotype

Rat IgG1

Recommend Isotype Controls

Rat IgG1 kappa, Isotype Control

Species Reactivity

Mouse

IC₅₀ & Target

CD1d

In Vitro

Anti-Mouse CD1d Antibody (19G11) inhibits the activation of invariant natural killer T (iNKT) cells in dendritic cells^[1].
Anti-Mouse CD1d Antibody (19G11) (10 μg/mL) blocks CD1d in MODE-K cells^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Anti-Mouse CD1d Antibody (19G11) (1 mg, i.p., before skin sensitization and before and 2 days after Oxazolone) reduces the severity of colitis in Oxazolone (HY-126360)-induced colitis mice^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Gene ID

12479 [NCBI]

Accession

P11609

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

Format

Product Image

Application

in vivo CD1d neutralization; in vitro CD1d neutralization

Chemical Information

Appearance Liquid
Molecular Weight 150 kDa
Color Colorless to light yellow
SMILES

[Anti-Mouse CD1d Antibody (19G11)]
Formulation

Please refer to the lot-specific COA for specific buffer information.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (256 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Inhibitory Antibodies User Guide (603 KB)

References

[1]. Melum E, et al. Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin. Nat Immunol. 2019 Dec;20(12):1644-1655. [Content Brief]

[2]. Olszak T, et al. Protective mucosal immunity mediated by epithelial CD1d and IL-10. Nature. 2014 May 22;509(7501):497-502. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- Description
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- IC₅₀ & Target
- In Vitro
- In Vivo
- Gene ID
- Accession
- Conjugated
- Reconsititution
- Format
- Application
Chemical Information
Purity & Documentation
References

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
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Purity:
Quantity:

Anti-Mouse CD1d Antibody (19G11)

HOLO Human Interleukin-2 (IL-2) Detection Kit

Bradford Protein Assay Kit

Protein A Agarose

Cell-ATP Viability Detection Kit

PBS Buffer (1×)

Cytotoxicity LDH Assay Kit

DPBS Buffer (1×)