Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
multiple-drug
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "multiple-drug" in MCE Product Catalog:
Target:
Research Areas:
NSC745885 an effective anti-tumor agent, shows selective toxicity against multiple cancer cell lines but not normal cells. NSC745885 is an effective down-regulator of EZH2 via proteasome-mediated degradation. NSC745885 provides possibilities for the study of advanced bladder and oral squamous cell carcinoma (OSCC) cancers .
Cat. No.: HY-P10378
Target:
Research Areas:
Cat. No.: HY-16371
CAS No.: 186348-23-2
Synonyms: IDN 5109; BAY 59-8862
Target:
Research Areas:
Ortataxel (IDN 5109; BAY 59-8862) is a derivative of Paclitaxel (HY-B0015). Ortataxel exhibits activity against multiple drug-sensitive and resistant cancer cell lines .
Cat. No.: HY-178985
HIV-1-IN-90 is a potent HIV inhibitor. HIV-1-IN-90 exhibits potent inhibitory activity against multiple drug-resistant HIV-1 strains with EC50s of 1.5-31 nM. HIV-1-IN-90 has good security. HIV-1-IN-90 can be used for research on HIV virus infection .
Cat. No.: HY-106852A
CAS No.: 133686-28-9
KP 736 sodium is a broad-spectrum antibacterial agent. KP 736 sodium exhibits excellent broad-spectrum anti Gram negative bacterial activity in vitro, especially effective against Pseudomonas aeruginosa and multiple drug-resistant bacteria. KP 736 sodium can be used for research on bacterial infections .
Cat. No.: HY-114957
CAS No.: 207736-05-8
Target:
Research Areas:
CI-1029 is a HIV-1 protease inhibitor with a human IC50 of 0.11 nM. CI-1029 inhibits both wild-type and mutant HIV proteases, and exhibits antiviral activity against HIV and multiple drug-resistant HIV strains, with an EC50 of 6.31 μM in the presence of 30% human serum. CI-1029 can be used in studies related to HIV infection and acquired immunodeficiency syndrome (AIDS) .
Cat. No.: HY-L225
259 compounds
Drug development is both expensive and time-consuming, with approximately one-third of drug discontinuations caused by severe adverse drug reactions (ADRs). Among these, drug-induced cardiotoxicity (DICT) is one of the primary reasons for late-stage clinical drug failures and market withdrawals. To date, cardiotoxicity has been observed in multiple drug classes, such as anticancer drugs, antipsychotics, antidepressants, antibiotics, and neurodegenerative disease medications. To reduce cardiac ADRs, it is crucial to determine the clinical relevance of DICT to treatment, elucidate the underlying molecular mechanisms, identify reliable biomarkers, and develop new diagnostic and therapeutic approaches.
MCE offers 259 cardiotoxicity compounds, including some FDA-approved drugs as well as inhibitors/blockers of the hERG potassium channel.
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
