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Results for "

pH-sensitive fluorescent probe

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

3

Fluorescent Dyes

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15940
    5(6)-Carboxyfluorescein
    5 Publications Verification

    5(6)-FAM; 5-(and-6)-Carboxyfluorescein mixed isomers

    		 Fluorescent Dye Cancer
    5(6)-Carboxyfluorescein (5(6)-FAM) is an amine-reactive pH-sensitive green fluorescent probe. 5(6)-Carboxyfluorescein (5(6)-FAM) can be used to label proteins, peptides and nucleotides. 5(6)-Carboxyfluorescein can be used for the detection of tumour areas in vivo .
    5(6)-Carboxyfluorescein
  • HY-D0077
    2',7'-Difluorofluorescein

    Oregon green 488

    		 Fluorescent Dye Others
    2',7'-Difluorofluorescein (Oregon green 488) is a fluorescein derivative and a pH-sensitive fluorescent probe (pKa ~4.7). Upon excitation at 488 nm, 2',7'-Difluorofluorescein exhibits pH-sensitive fluorescence intensity through the formation of dianions, while its pH sensitivity decreases under excitation at 450 nm, allowing its use in ratiometric pH analysis. 2',7'-Difluorofluorescein can be used for the quantitative analysis of pH values in the range of 2-7 in submicron aerosol particles. 2',7'-Difluorofluorescein undergoes buffer-mediated and buffer-free excited-state proton transfer between different protonated forms, and its cationic form undergoes rapid excited-state deprotonation. 2',7'-Difluorofluorescein is resistant to photodegradation, maintains stable absorption and fluorescence properties within the physiological pH range, and serves as a fluorescent protein label, a component of Ca 2+ indicators, a fluorescent imaging agent, and an anisotropy probe .
    2',7'-Difluorofluorescein
  • HY-124473
    Naphthofluorescein

    NapHthafluorescein

    		 HIF/HIF Prolyl-Hydroxylase Cancer
    Naphthofluorescein inhibits the interaction between HIF-1 and Mint3. Naphthofluorescein suppresses Mint3-dependent HIF-1 activity and glycolysis in cancer cells and macrophages without cytotoxicity in vitro and adverse effect in vivo . Naphthofluorescein is also a fluorescent pH-sensitive probe that can be used for functional Cerenkov imaging .
    Naphthofluorescein
  • HY-118155
    9-Amino-6-chloro-2-methoxyacridine
    2 Publications Verification

    ACMA

    		 Fluorescent Dye Others
    9-Amino-6-chloro-2-methoxyacridine is a pH sensitive fluorescent probe. 9-Amino-6-chloro-2-methoxyacridine has been frequently used to measure changes in vacuolar pH when a specific substrate crosses the tonoplast through a putative H +/solute antiport system .
    9-Amino-6-chloro-2-methoxyacridine
  • HY-W110898
    Nile blue chloride

    		Fluorescent Dye Others
    Nile blue chloride is a highly fluorescent and photostable organic dye. Nile blue chloride and fluorescein isothiocyanate (FITC) can be used to construct a ratiometric pH sensitive probe for tracking the pH of the extracellular fluid between cancer cells in realtime. Nile Blue chloride has the potential for the research of nonlinear optics .
    Nile blue chloride
  • HY-157036
    INSA

    		Fluorescent Dye Others
    INSA is a a pH-sensitive fluorescent probe. INSA can simultaneously light up mitochondria (red emission) and lysosomes (green emission) for their internal pH differences .
    INSA

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