1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. Calcium Channel
  3. sFTX-3.3

sFTX-3.3 

Cat. No.: HY-131942
Handling Instructions

sFTX-3.3 is a Ca2+ channel antagonist with IC50s of approximately 0.24 mM and 0.70 mM against P-type and N-type channels.

For research use only. We do not sell to patients.

sFTX-3.3 Chemical Structure

sFTX-3.3 Chemical Structure

CAS No. : 141997-14-0

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Description

sFTX-3.3 is a Ca2+ channel antagonist with IC50s of approximately 0.24 mM and 0.70 mM against P-type and N-type channels[1][2].

IC50 & Target

P-type calcium channel

0.24 mM (IC50)

N-Type Ca2+ Channel

0.70 mM (IC50)

In Vitro

sFTX-3.3 (100 μM) reduces the duration of the slow component of presynaptic calcium currents by about 50% of the control and also reduces presynaptic sodium current by approximately 20% of the control. sFTX-3.3 (100 μM) reduces whole-cell sodium current recorded from SK.N.SH cells by approximately 15%[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

287.40

Formula

C₁₂H₂₉N₇O

CAS No.

141997-14-0

SMILES

O=C(NCCCNCCCN)[[email protected]@H](N)CCCNC(N)=N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

sFTX-3.3Calcium ChannelCa2+ channelsCa channelsInhibitorinhibitorinhibit

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Cat. No.:
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