1. Anti-infection
  2. HIV
  3. Tsugafolin

Tsugafolin (compound 4) is a dehydroflavone with weak anti-HIV activity (IC50=118 μM) and devoid cytotoxicity (<150 μM). Tsugafolin can be isolated from Vitex leptobotrys.

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Tsugafolin

Tsugafolin 화학구조

CAS No. : 66568-97-6

사이즈 가격 재고 수량
1 mg 견적 받기 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
5 mg 견적 받기 2 - 3 weeks 1 - 2 weeks 3 - 4 weeks 2 - 3 weeks
10 mg   견적 받기  
50 mg   견적 받기  
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고객리뷰

Based on 1 publication(s) in Google Scholar

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제품 설명

Tsugafolin (compound 4) is a dehydroflavone with weak anti-HIV activity (IC50=118 μM) and devoid cytotoxicity (<150 μM). Tsugafolin can be isolated from Vitex leptobotrys[1].

Cellular Effect
Cell Line Type Value Description References
HEp-2 IC50
154.4 μM
Compound: 6
Antiviral activity against Parainfluenza virus type 3 infected in human Hep2 cells assessed as inhibition of virus-induced cytopathogenic effect by plaque reduction assay
Antiviral activity against Parainfluenza virus type 3 infected in human Hep2 cells assessed as inhibition of virus-induced cytopathogenic effect by plaque reduction assay
[PMID: 19267453]
HEp-2 IC50
77 μM
Compound: 6
Antiviral activity against Respiratory syncytial virus infected in human Hep2 cells assessed as inhibition of virus-induced cytopathogenic effect by plaque reduction assay
Antiviral activity against Respiratory syncytial virus infected in human Hep2 cells assessed as inhibition of virus-induced cytopathogenic effect by plaque reduction assay
[PMID: 19267453]
MDCK IC50
308.5 μM
Compound: 6
Antiviral activity against Influenza A virus infected in MDCK cells assessed as inhibition of virus-induced cytopathogenic effect by plaque reduction assay
Antiviral activity against Influenza A virus infected in MDCK cells assessed as inhibition of virus-induced cytopathogenic effect by plaque reduction assay
[PMID: 19267453]
분자량

300.31

화학식

C17H16O5

CAS No.
SMILES

O=C1C[C@@H](C2=CC=C(OC)C=C2)OC3=CC(O)=CC(OC)=C13

Structure Classification
Initial Source
선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서
References
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
Tsugafolin
Cat. No.:
HY-N1116
수량:
MCE Japan Authorized Agent: