Ptpn22 - protein tyrosine phosphatase, non-receptor type 22 Gene

Also Known as Ptpn8

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 295338

Summary

Enables protein tyrosine kinase binding activity. Involved in regulation of calcium ion transmembrane transport and regulation of peptidyl-tyrosine phosphorylation. Located in cytoplasm. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including Addison's disease; Meniere's disease; autoimmune disease (multiple); chronic lymphocytic leukemia; and pulmonary tuberculosis. Orthologous to human PTPN22 (protein tyrosine Phosphatase non-receptor type 22). [provided by Alliance of Genome Resources, Apr 2022]

Ptpn22 Products (2)

mRNA Protein Name
NM_001106460.1 NP_001099930.1 tyrosine-protein phosphatase non-receptor type 22
NM_001106460.1 NP_001099930.1 tyrosine-protein phosphatase non-receptor type 22
Protein Preferred Names Protein Names

tyrosine-protein phosphatase non-receptor type 22

  • protein tyrosine phosphatase, non-receptor type 22 (lymphoid)

  • protein tyrosine phosphatase, non-receptor type 8

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-139693 PTPN22-IN-1 Inhibitor 99.60% Unkown
HY-156659 NC1 Inhibitor 98.73% Unkown
HY-155848 LYP-IN-4 Inhibitor 98.60% Unkown
HY-170564 PTPN22-IN-2 Inhibitor / Unkown
HY-183573 PTPRO-IN-1 Inhibitor / Unkown
HY-184931 PTPN22-IN-3 / Unkown
HY-RS11424 PTPN22 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17516 Ptpn22 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23973 Ptpn22 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptpn22 NCBI NCBI:26191