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Cat. No.: HY-170564

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PTPN22-IN-2

PTPN22-IN-2 (Compound 8b-19) is a PTPN22 inhibitor with an IC₅₀ of 250 nM. PTPN22-IN-2 can be used for research in the field of immunomodulation.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₂₈H₂₂ClNO₆
분자량:503.93

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

PTPN22-IN-2 Chemical Structure

사이즈

가격

재고

수량

Amount: USD 0.00

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

PTPN22-IN-2 (Compound 8b-19) is a PTPN22 inhibitor with an IC₅₀ of 250 nM. PTPN22-IN-2 can be used for research in the field of immunomodulation^[1].

Chemical Information

분자량 503.93
화학식 C₂₈H₂₂ClNO₆
SMILES

OC1=C(C(O)=O)C=C(C(/C=C/C2=CC=CC(Cl)=C2)=C(C3=CC=C(OCC(NC4CC4)=O)C=C3)O5)C5=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jassim BA, et al. Structure-activity relationship studies and design of a PTPN22 inhibitor with enhanced isozyme selectivity and cellular efficacy. Eur J Med Chem. 2025 Feb 5;283:117129. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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