Ttk - Ttk protein kinase Gene

Also Known as Mps1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 315852

Summary

Predicted to enable identical protein binding activity; kinetochore binding activity; and protein kinase activity. Predicted to be involved in several processes, including negative regulation of metaphase/anaphase transition of cell cycle; peptidyl-serine phosphorylation; and protein localization to kinetochore. Predicted to act upstream of or within female meiosis chromosome segregation; protein localization to organelle; and protein phosphorylation. Predicted to be located in cytoplasm. Predicted to be active in kinetochore; nucleus; and spindle. Orthologous to human TTK (TTK protein kinase). [provided by Alliance of Genome Resources, Apr 2022]

Ttk Products (2)

mRNA Protein Name
NM_001108172.1 NP_001101642.1 dual specificity protein kinase TTK isoform 2
NM_001401052.1 NP_001387981.1 dual specificity protein kinase TTK isoform 1
Protein Preferred Names Protein Names

dual specificity protein kinase TTK

  • Monopolar spindle 1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-101340A Luvixasertib hydrochloride Inhibitor 99.63% Phase 2
HY-143904 PROTAC TTK degrader-1 Degrader 98.01% Phase 2
HY-101340 Luvixasertib Inhibitor 99.9600% Phase 1

Pre-clinical Phase

Bioactive Molecules (27)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-116673 TTK21 Activator 99.39% Unkown
HY-14710 AZ3146 Inhibitor 99.42% Unkown
HY-108709 CC-671 Inhibitor 99.06% Unkown
HY-171770 dAurAB5 99.03% Unkown
HY-168543 PROTAC MPS1 degrader 2 Degrader 99.78% Unkown
HY-19544 JAK3-IN-1 Inhibitor 99.31% Unkown
HY-100024 NTRC 0066-0 Inhibitor 99.02% Unkown
HY-149213 LSD1/TLK1-IN-1 99.20% Unkown
HY-168540 PROTAC MPS1 degrader 1 Degrader 99.90% Unkown
HY-168542 TTK ligand 2 Ligand 99.43% Unkown
HY-168545 TTK ligand 3 99.50% Unkown
HY-144308 RMS-07 Inhibitor / Unkown
HY-132884 TTK inhibitor 3 Inhibitor / Unkown
HY-110347 Mps1-IN-1 dihydrochloride Inhibitor / Unkown
HY-116190 CFI-401870 Inhibitor / Unkown
HY-123675 CFI-400936 Inhibitor / Unkown
HY-143905 PROTAC TTK degrader-2 Degrader / Unkown
HY-160419 Mps1-IN-8 Inhibitor / Unkown
HY-162156 TTK inhibitor 4 Inhibitor / Unkown
HY-164955 TTK/PLK1-IN-1 Inhibitor / Unkown
HY-179430 TTK-IN-5 Inhibitor / Unkown
HY-182928 LRRK2-IN-21 Inhibitor / Unkown
HY-RS15226 TTK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-116470 Mps1/TTK-IN-1 Inhibitor / Unkown
HY-RS16792 Ttk Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21071 Ttbk2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23232 Ttk Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ttk NCBI NCBI:7272