TTK/PLK1-IN-1
TTK/PLK1-IN-1 (Formula I) is the inhibitor for threonine tyrosine kinase (TTK) and polo-like kinase 1 (PLK1) with IC50 of 7 nM and 72 nM. TTK/PLK1-IN-1 regulates spindle assembly checkpoint (SAC), and exhibits antitumor efficacy against TNBC.
For research use only. We do not sell to patients.
- CAS No.: 1817791-70-0
- Formula: C30H33N7O2
- Molecular Weight:523.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 7 nM (threonine tyrosine kinase); 72 nM (polo-like kinase 1)
Chemical Information
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CAS No. 1817791-70-0
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Molecular Weight 523.63
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Formula C30H33N7O2
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SMILES
O=C(C1=C2CCC3=CN=C(NC4=CC=C(N5CCNCC5)C=C4OC)N=C3N2C=C1)NC6=C(C)C=CC=C6C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)