1817791-70-0

TTK/PLK1-IN-1 Chemical Structure
1817791-70-0

Chemical Structure

TTK/PLK1-IN-1

  • CAS No.: 1817791-70-0
  • Formula:C30H33N7O2
  • Molecular Weight:523.63

InChIKey: UYPNZGVGCJECJV-UHFFFAOYSA-N

SMILES: O=C(C1=C2CCC3=CN=C(NC4=CC=C(N5CCNCC5)C=C4OC)N=C3N2C=C1)NC6=C(C)C=CC=C6C

Biological Activity: TTK/PLK1-IN-1 (Formula I) is the inhibitor for threonine tyrosine kinase (TTK) and polo-like kinase 1 (PLK1) with IC50 of 7 nM and 72 nM. TTK/PLK1-IN-1 regulates spindle assembly checkpoint (SAC), and exhibits antitumor efficacy against TNBC[1].

Cat. No. Product Name Purity Description Pricing
HY-164955 		TTK/PLK1-IN-1 TTK/PLK1-IN-1 (Formula I) is the inhibitor for threonine tyrosine kinase (TTK) and polo-like kinase 1 (PLK1) with IC50 of 7 nM and 72 nM. TTK/PLK1-IN-1 regulates spindle assembly checkpoint (SAC), and exhibits antitumor efficacy against TNBC.
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