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Cat. No.: HY-N15756

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N-Demethylsinomenine

N-Demethylsinomenine is a morphinane alkaloid that can be isolated from Sinomenium acutum. N-Demethylsinomenine has a protective effect against H₂O₂-induced cell injury. N-Demethylsinomenine can be used in the research of diseases such as Alzheimer's disease.

For research use only. We do not sell to patients.

CAS No.: 240131-71-9
Formula: C₁₈H₂₁NO₄
Molecular Weight:315.36

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

N-Demethylsinomenine Chemical Structure

CAS No.: 240131-71-9

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC₅₀	>100 μM Compound: 3	Cytotoxicity against mouse RAW264.7 cells after 24 hrs by MTT assay Cytotoxicity against mouse RAW264.7 cells after 24 hrs by MTT assay	[PMID: 21530276]

Chemical Information

CAS No. 240131-71-9
Molecular Weight 315.36
Formula C₁₈H₂₁NO₄
SMILES

O=C1C[C@]2(CCN3)[C@]([C@@H]3CC(C2=C4O)=CC=C4OC)([H])C=C1OC
Structure Classification
- Alkaloids
- Other Alkaloids
Initial Source
- Plants
- Menispermaceae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bao GH, et al. Morphinane alkaloids with cell protective effects from Sinomenium acutum. J Nat Prod. 2005 Jul;68(7):1128-30. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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